20.500.12556/DKUM-97083 Per- in polifluoroalkilne snovi (PFAS) v pitni vodi: etiologija onesnaženja in učinki na javno zdravje Per- and polyfluoroalkyl substances (PFAS) in drinking water: etiology of contamination and effects on public health Uvod: Per- in polifluoroalkilne snovi (PFAS) so obstojne sintetične kemikalije, ki se zaradi široke industrijske in potrošniške uporabe pogosto pojavljajo v okolju, vključno s pitno vodo. Zaradi svoje obstojnosti, bioakumulacijskega potenciala in povezanosti z različnimi škodljivimi učinki na zdravje ljudi predstavljajo pomemben izziv za javno zdravje. Namen zaključnega dela je pregledati vire PFAS v pitni vodi, poti onesnaženja ter vplive izpostavljenosti na zdravje ljudi. Metode: Raziskava temelji na »scoping« pregledu znanstvene literature. Sistematično iskanje je potekalo v podatkovnih bazah PubMed, CINAHL in Web of Science. Pri iskanju literature smo upoštevali PRISMA priporočila. Podatki so bili analizirani s kvalitativnim pristopom in tematsko analizo. Rezultati: S sistematičnim iskanjem literature smo identificirali 214 zadetkov. Po odstranitvi duplikatov ter pregledu naslovov in povzetkov je bilo v končno analizo vključenih 35 raziskovalnih člankov. Razprava in zaključek: PFAS v pitni vodi izhajajo predvsem iz industrijskih izpustov, uporabe pen za gašenje požarov, čistilnih naprav in drugih virov ter se pojavljajo v različnih virih pitne vode. Izpostavljenost PFAS lahko vpliva na imunski sistem, hormonsko ravnovesje in razvoj otrok, zato so za zaščito prebivalstva ključni spremljanje, regulacija, učinkovita priprava vode in ozaveščanje javnosti. Introduction: Per- and polyfluoroalkyl substances (PFAS) are persistent synthetic chemicals widely used in industrial and consumer products and frequently detected in drinking water. Due to their environmental persistence, bioaccumulation potential, and links to adverse health effects, PFAS pose a significant public health concern. This study aimed to review sources of PFAS in drinking water, contamination pathways, and impacts on human health to support improved risk understanding and regulation. Methods: A scoping review of scientific literature was conducted. Relevant studies were systematically identified in the PubMed, CINAHL, and Web of Science databases. When searching the literature, we followed the PRISMA recommendations. Data were analyzed using a qualitative approach with thematic analysis. Results: The literature search identified 214 records. After removing duplicates and screening titles and abstracts, 38 full-text articles were assessed for eligibility. Thirty-five research articles met the inclusion criteria and were included in the final analysis. Discussion and conclusion: PFAS in drinking water originate mainly from industrial discharges, firefighting foams, wastewater treatment plants, and other contamination sources, and may occur in various drinking water supplies. Exposure may affect the immune system, hormonal balance, and child development, emphasizing the importance of monitoring, regulation, water treatment, and public awareness. per- in polifluoroalkilne snovi (PFAS) pitna voda javno zdravje izpostavljenost ljudi per- and polyfluoroalkyl substances (PFAS) drinking water public health human exposure true false false [N. Jurić] Slovenski jezik Angleški jezik Magistrsko delo/naloga 2026-02-17 10:49:06 2026-04-15 16:50:38 2026-04-16 03:08:09 0000-00-00 00:00:00 2026 0 Maribor 0 0000-00-00 NiDoloceno NiDoloceno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 556.114.7:502.51:504.5:614(043.2) 271258115 MAG_Juric_Natasa_2026.pdf MAG_Juric_Natasa_2026.pdf 1 9A101DCBCBBC0B372E1E5F33E056900C 713d15d13f6381073e57d112cff2d8e7ca6bcc6ffb6afae7f0900d80311c9f3f a3e48820-0be9-11f1-aedc-00155d580e1a https://dk.um.si/Dokument.php?lang=slv&id=203404 Fakulteta za zdravstvene vede 0 0 0