20.500.12556/DKUM-97586 Vpliv vrste torakalnega drena na učinkovitost drenaže in potek pooperativnega zdravljenja po videotorakoskopski lobektomiji pljuč: primerjava silikonskih s standardnimi pvc dreni Impact of chest drain type on drainage efficiency and postoperative treatment outcome after video-assisted thoracoscopic surgery lobectomy: a comparison of silicone and standard PVC drains Torakalni dren se po videotorakoskopskih (VATS) resekcijah pljuč rutinsko uporablja za odstranjevanje tekočine in zraka iz plevralnega prostora. Namen doktorske naloge je bil primerjati vpliv koaksialnih silikonskih drenov in standardnih polivinilkloridnih (PVC) drenov na pooperativno bolečino, učinkovitost drenaže in kratkoročni izid pooperativnega zdravljenja po VATS lobektomiji pljuč. V prospektivno randomizirano raziskavo smo vključili 80 preiskovancev, ki so imeli opravljeno VATS lobektomijo pljuč zaradi raka. Štirideset preiskovancev je imelo po operaciji vstavljen koaksialni silikonski dren (intervencijska skupina), preostalih 40 pa standardni PVC dren (kontrolna skupina). Pooperativno bolečino v prvih dveh dneh po operaciji smo ocenjevali s porabo analgetikov, meritvami moči dihalnih mišic (maksimalni inspiratorni tlak [MIP] in maksimalni ekspiratorni tlak [MEP]) ter z vidno analogno lestvico (VAS). MIP, MEP in VAS smo merili v mirovanju in ob telesni dejavnosti. V končno analizo je bilo vključenih 69 preiskovancev: 35 v intervencijski skupini in 34 v kontrolni. Skupini sta bili primerljivi po učinkovitosti drenaže in kratkoročnem izidu zdravljenja, primarni izid, poraba metamizola, pa ni dosegel statistične značilnosti. Kljub temu so sekundarni in podporni izidi ocene bolečine nakazovali ugodnejši pooperativni potek v intervencijski skupini, z manjšo porabo preostalih analgetikov ob primerljivi intenzivnosti bolečine ter bolje ohranjeno močjo dihalnih mišic. Ugotovitve delno podpirajo predpostavko o ugodnejšem vplivu uporabe silikonskih drenov na pooperativno bolečino in utemeljujejo potrebo po nadaljnjih raziskavah. Chest drain are routinely used after video-assisted thoracoscopic surgery (VATS) lung resections to evacuate air and fluid from the pleural space. The aim of this doctoral thesis was to compare the impact of coaxial silicone drains and standard polyvinyl chloride (PVC) drains on postoperative pain, drainage efficacy, and short-term treatment outcome following VATS lobectomy. The prospective randomized study included 80 subjects who underwent VATS lobectomy for lung cancer. Forty subjects received a coaxial silicone drain following surgery (intervention group), while the remaining 40 were fitted with a standard PVC drain (control group). Postoperative pain during the first two postoperative days was evaluated by assessing analgesic consumption, respiratory muscle strength (measured as maximal inspiratory pressure [MIP] and maximal expiratory pressure [MEP]), and the visual analog scale (VAS). MIP, MEP, and VAS were measured at rest and during physical activity. A total of sixty-nine subjects were included in the final analysis: 35 in the intervention group and 34 in the control group. The two groups were comparable in terms of drainage efficiency and short-term treatment outcomes; however, the primary outcome, metamizole consumption, did not reach statistical significance. Nevertheless, secondary and supportive outcomes of pain assessment consistently indicated a more favorable postoperative course in the intervention group, with lower consumption of other analgesics at comparable pain intensity and better preservation of respiratory muscle strength. These results partially support the hypothesis of a more favorable effect of the use of silicone drains on postoperative pain and justify the need for further research. videoasistirana torakoskopska kirurgija (VATS) lobektomija pljuč pooperativna bolečina torakalni dren analgezija video-assisted thoracoscopic surgery (VATS) lobectomy postoperative pain chest drain analgesia true true false [B. Greif] Slovenski jezik Angleški jezik Doktorska disertacija 2026-03-23 11:50:01 2026-07-14 11:06:29 2026-07-15 03:10:04 0000-00-00 00:00:00 2026 0 Maribor 0 0000-00-00 NiDoloceno NiDoloceno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 616.24-006-089.168/-089.48:615.46(043.3) 284688131 DOK_Greif_Boris_2026.pdf DOK_Greif_Boris_2026.pdf 1 B2AA17DDCF4C8EDC9CDFBA2235FA319E b88c90dd41f306d8b2de71a936441fc17acfa0d6dfa6b9f634d8cd7c8617117f 2068e635-7526-11f1-9647-00155d580e34 https://dk.um.si/Dokument.php?lang=slv&id=207768 Medicinska fakulteta 0 0 0