20.500.12556/DKUM-97712 Verifikacija merilnih metod za določanje analitov v serumu na biokemičnem analizatorju magistrsko delo Verification of measurement methods for the determination of analytes in serum on a biochemical analyzer V nalogi smo izvedli verifikacijo merilnih metod za izbrane biokemijske analite, ki so pomembni v diagnostiki anemij. To so železo, feritin, vitamin B12 in folati. Meritve smo izvajali na analizatorju Atellica CI Analyzer in rezultate primerjali z obstoječim analizatorjem Dimension EXL 200. Z uporabo kontrolnih materialov in vzorci preiskovancev smo ocenili natančnost, ponovljivost, točnost in primerljivost meritev. Statistična analiza je vključevala opisno statistiko, test normalnosti porazdelitev, statistične teste za primerjavo med skupinami meritev, korelacijsko analizo in Blant-Altmanovo metodo. Rezultati so pokazali dobro ujemanje med analizatorjema ter skladnost z zahtevami proizvajalca, kar potrjuje, da analizator Atellica zagotavlja zanesljive in klinično uporabne rezultate. Na podlagi ugotovitev je analizator primeren za uvedbo v rutinsko laboratorijsko diagnostiko. In this study, we verified measurement methods for selected biochemical analytes important in the diagnosis of anaemia, namely iron, ferritin, vitamin B12, and folates. Measurements were performed using the Atellica CI Analyzer, and the results were compared with those obtained from the existing Dimension EXL 200. Using control materials and patient samples, we evaluated the precision, repeatability, accuracy, and comparability of the measurements. Statistical analysis included descriptive statistics, tests of normality, statistical tests for comparison between measurement groups, correlation analysis, and the Bland-Altman method. The results showed good agreement between the two analysers and compliance with the manufacturer’s specifications, confirming that the Atellica analyser provides reliable and clinically applicable results. Based on these findings, the analyser is suitable for implementation in routine laboratory diagnostics. Verifikacija statistika natančnost točnost anemija. Verification statistics precison accuracy anemia. true true false [S. Veranič] Slovenski jezik Angleški jezik Magistrsko delo/naloga 2026-04-06 11:53:03 2026-05-04 10:43:53 2026-05-07 03:10:25 0000-00-00 00:00:00 2026 0 Maribor 0 Maribor 1 spletni vir (1 datoteka PDF (XI, 57 str.)) 0000-00-00 NiDoloceno NiDoloceno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 577.087.1(043.2) 277174787 MAG_Veranic_Simona_2026.pdf MAG_Veranic_Simona_2026.pdf 1 49E7811354D769904C35DFA203D1F817 c07e2647cdabd332781859393ec399d30d5d8e3eac80adfc26ca3404ddd84861 144d4f2d-4794-11f1-89cf-00155d0001a1 https://dk.um.si/Dokument.php?lang=slv&id=205712 Fakulteta za kemijo in kemijsko tehnologijo 0 0 0