20.500.12556/DKUM-99947 Odstranjevanje antibiotikov z novo zasnovanimi magnetnimi nanodelci, prevlečenimi s slojem polisaharidov Removal of antibiotics using newly designed magnetic nanoparticles coated with a polysaccharide layer Naraščajoča prisotnost antibiotičnih onesnaževal v vodnem okolju predstavlja pomembno tveganje za zdravje ljudi in ekosisteme, zato je potreben razvoj naprednih postopkov njihovega odstranjevanja. V okviru magistrskega dela smo sintetizirali magnetne nanodelce železovih oksidov (MNPs) z metodo koprecipitacije ter jih funkcionalizirali s kvaternizirano celulozo (qC). Pripravljeni nanoadsorbent MNPs@qC smo ovrednotili za adsorpcijsko odstranjevanje metronidazola (MNZ) iz vodnih raztopin. Karakterizacijo nanomaterialov smo izvedli z različnimi fizikalno-kemijskimi karakterizacijskimi metodami, s katerimi smo potrdili uspešno funkcionalizacijo MNPs s qC ter ohranitev njihove magnetne odzivnosti. Adsorpcijski poskusi so pokazali, da MNPs@qC omogoča učinkovitejše odstranjevanje antibiotika MNZ v primerjavi z nefunkcionaliziranimi MNPs, pri čemer je bila največja učinkovitost dosežena pri pH 3. Kot najprimernejša sta bila izbrana masa adsorbenta 10 mg in kontaktni čas 120 min, kjer je bila dosežena adsorpcijska kapaciteta 8,4 mg/g. Kinetične raziskave so pokazale najboljše ujemanje z modelom psevdo-drugega reda (R2 = 0,9855), kar nakazuje pomembno vlogo interakcij med molekulami MNZ in funkcionalnimi skupinami na površini nanoadsorbenta. Langmuirjev izotermni model je pokazal najboljše prileganje eksperimentalnim podatkom (R2 = 0,9892), kar nakazuje pretežno monoplastno adsorpcijo na omejenem številu vezavnih mest. Uporabnost adsorbenta smo preverili tudi v realnem sistemu, kjer smo v pitno vodo dodali 20 μg/mL MNZ. Po adsorpciji metronidazola v času 120 min in realnem pH=3 smo dosegli adsorpcijsko kapaciteto 11,9 mg/g in 54,93 % učinkovitost odstranitve. Rezultati potrjujejo potencial MNPs@qC kot magnetno ločljivega in ponovno uporabnega nanoadsorbenta za odstranjevanje MNZ iz vodnih sistemov. The increasing presence of antibiotic contaminants in the aquatic environment poses a significant risk to human health and ecosystems, highlighting the need for the development of advanced removal processes. In this work, magnetic iron oxide nanoparticles (MNPs) were synthesized by the co-precipitation method and functionalized with quaternized cellulose (qC). The prepared MNPs@qC nanoadsorbent was evaluated for the adsorptive removal of metronidazole (MNZ) from aqueous solutions. The nanomaterials were characterized using various physicochemical characterization techniques, which confirmed the successful functionalization of the MNPs with qC while preserving their magnetic responsiveness. Adsorption experiments showed that MNPs@qC enabled more efficient removal of antibiotic MNZ compared with non-functionalized MNPs, with the highest removal efficiency achieved at pH 3. An adsorbent mass of 10 mg and a contact time of 120 min were selected as the most suitable conditions, under which an adsorption capacity of 8.4 mg/g was achieved. Kinetic studies showed the best fit to the pseudo-second-order model (R² = 0.9855), indicating an important role of interactions between MNZ molecules and the functional groups on the nanoadsorbent surface. The Langmuir isotherm model showed the best fit to the experimental data (R² = 0.9892), suggesting predominantly monolayer adsorption on a limited number of binding sites. The applicability of the nanoadsorbent was also evaluated in a real water system by spiking drinking water with 20 μg/mL MNZ. After 120 min of adsorption at the pH 3, an adsorption capacity of 11.9 mg/g and a removal efficiency of 54.93% were achieved. The results demonstrate the potential of MNPs@qC as a magnetically separable and reusable adsorbent for the removal of MNZ from aqueous systems. adsorpcija magnetni nanodelci kvaternizirana celuloza metronidazol odstranjevanje antibiotikov iz vode adsorption magnetic nanoparticles quaternized cellulose metronidazole antibiotic removal from aqueous solutions true true false Slovenski jezik Angleški jezik Magistrsko delo/naloga 2026-08-31 15:02:42 2026-09-18 10:54:15 2026-09-19 03:06:30 0000-00-00 00:00:00 2026 0 Maribor 0 0000-00-00 NiDoloceno NiDoloceno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 MAG_Krautic_Anja_2026.pdf MAG_Krautic_Anja_2026.pdf 1 CFD21D173D79F7249835659C72B6D093 a7d3f3ce6666d0b59e4145530735b081a82c0567eafa0a35e5a013dbe6b50f42 7464e2e6-b2bd-11f1-9651-00155d0001be https://dk.um.si/Dokument.php?lang=slv&id=212799 Fakulteta za kemijo in kemijsko tehnologijo 0 0 0