| Naslov: | Highly divergent Clostridium difficile strains isolated from the environment |
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| Avtorji: | ID Janežič, Sandra (Avtor)
ID Potočnik, Mojca (Avtor)
ID Tkalec, Valerija (Avtor)
ID Rupnik, Maja (Avtor) |
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| Datoteke: |  PLOS_ONE_2016_Janezic_et_al._Highly_Divergent_Clostridium_difficile_Strains_Isolated_from_the_Environment.pdf (1,13 MB)
MD5: 0D0D39BC7675501C5F2F4DB19F13A84E
 http://dx.plos.org/10.1371/journal.pone.0167101
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| Jezik: | Angleški jezik |
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| Vrsta gradiva: | Znanstveno delo |
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| Tipologija: | 1.01 - Izvirni znanstveni članek |
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| Organizacija: | MF - Medicinska fakulteta
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| Opis: | Clostridium difficile is one of the most important human and animal pathogens. However, the bacterium is ubiquitous and can be isolated from various sources. Here we report the prevalence and characterization of C. difficile in less studied environmental samples, puddle water (n = 104) and soil (n = 79). C. difficile was detected in 14.4% of puddle water and in 36.7% of soil samples. Environmental strains displayed antimicrobial resistance patterns comparable to already published data of human and animal isolates. A total of 480 isolates were grouped into 34 different PCR ribotypes. More than half of these (52.9%; 18 of 34) were already described in humans or animals. However, 14 PCR ribotypes were new in our PCR ribotype library and all but one were non-toxigenic. The multilocus sequence analysis of these new PCR ribotypes revealed that non-toxigenic environmental isolates are phylogenetically distinct and belong to three highly divergent clades, two of which have not been described before. Our data suggest that environment is a potential reservoir of genetically diverse population of C. difficile. |
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| Ključne besede: | clostridium difficile, environment, isolation |
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| Status publikacije: | Objavljeno |
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| Verzija publikacije: | Objavljena publikacija |
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| Leto izida: | 2016 |
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| Št. strani: | str. 1-12 |
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| Številčenje: | Letn. 11, št. 11 |
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| PID: | 20.500.12556/DKUM-66279  |
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| ISSN: | 1932-6203 |
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| UDK: | 579.852.13 |
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| COBISS.SI-ID: | 512659256 |
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| DOI: | 10.1371/journal.pone.0167101 |
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| ISSN pri članku: | 1932-6203 |
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| NUK URN: | URN:SI:UM:DK:R56Y6X6C |
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| Datum objave v DKUM: | 19.06.2017 |
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| Število ogledov: | 1773 |
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| Število prenosov: | 425 |
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| Metapodatki: |    |
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| Področja: | Ostalo
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