| Naslov: | Low overlap between carbapenem resistant Pseudomonas aeruginosa genotypes isolated from hospitalized patients and wastewater treatment plants |
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| Avtorji: | ID Golle, Andrej (Avtor)
ID Janežič, Sandra (Avtor)
ID Rupnik, Maja (Avtor) |
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| Datoteke: |  PLOS_ONE_2017_Golle,_Janezic,_Rupnik_Low_overlap_between_carbapenem_resistant_Pseudomonas_aeruginosa_genotypes_isolated_from_hospitalize.pdf (2,44 MB)
MD5: 981A40A1145757F001D31DD89EF720E4
PID: 20.500.12556/dkum/a3cc2d27-c952-4d7f-9cf9-f1c21d0e0e3b
 http://dx.plos.org/10.1371/journal.pone.0186736
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| Jezik: | Angleški jezik |
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| Vrsta gradiva: | Znanstveno delo |
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| Tipologija: | 1.01 - Izvirni znanstveni članek |
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| Organizacija: | MF - Medicinska fakulteta
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| Opis: | The variability of carbapenem-resistant Pseudomonas aeruginosa strains (CRPA) isolated from urine and respiratory samples in a large microbiological laboratory, serving several health care settings, and from effluents of two wastewater treatment plants (WWTP) from the same region was assessed by PFGE typing and by resistance to 10 antibiotics. During the 12-month period altogether 213 carbapenem-resistant P. aeruginosa isolates were cultured and distributed into 65 pulsotypes and ten resistance profiles. For representatives of all 65 pulsotypes 49 different MLSTs were determined. Variability of clinical and environmental strains was comparable, 130 carbapenem-resistant P. aeruginosa obtained from 109 patients were distributed into 38 pulsotypes, while 83 isolates from WWTPs were classified into 31 pulsotypes. Only 9 pulsotypes were shared between two or more settings (hospital or WWTP). Ten MLST were determined for those prevalent pulsotypes, two of them (ST111 and ST235) are among most successful CRPA types worldwide. Clinical and environmental carbapenem-resistant P. aeruginosa strains differed in antibiotic resistance. The highest proportion of clinical isolates was resistant to piperacillin/tazobactam (52.3%) and ceftazidime (42.3%). The highest proportion of environmental isolates was resistant to ceftazidime (37.1%) and ciprofloxacin (35.5%). The majority of isolates was resistant only to imipenem and/or meropenem. Strains with additional resistances were distributed into nine different patterns. All of them included clinically relevant strains, while environmental strains showed only four additional different patterns. |
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| Ključne besede: | carpabenem resistance, antibiotic resistance, Pseudomonas aeruginosa, isolates |
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| Status publikacije: | Objavljeno |
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| Verzija publikacije: | Objavljena publikacija |
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| Leto izida: | 2017 |
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| Št. strani: | str. 1-13 |
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| Številčenje: | Letn. 12, št. 10 |
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| PID: | 20.500.12556/DKUM-69225  |
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| ISSN: | 1932-6203 |
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| UDK: | 579.61 |
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| COBISS.SI-ID: | 512751672 |
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| DOI: | 10.1371/journal.pone.0186736 |
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| ISSN pri članku: | 1932-6203 |
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| NUK URN: | URN:SI:UM:DK:EAKSFZKP |
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| Datum objave v DKUM: | 12.12.2017 |
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| Število ogledov: | 2281 |
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| Število prenosov: | 526 |
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| Metapodatki: |    |
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| Področja: | Ostalo
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