| Naslov: | Ozonation of amoxicillin and ciprofloxacin in model hospital wastewater to increase biotreatability |
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| Avtorji: | ID Aleksić, Severina (Avtor)
ID Žgajnar Gotvajn, Andreja (Avtor)
ID Premzl, Katarina (Avtor)
ID Kolar, Mitja (Avtor)
ID Šostar-Turk, Sonja (Avtor) |
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| Datoteke: |  Aleksic-2021-Ozonation_of_Amoxicillin_and_Cipr.pdf (1,96 MB)
MD5: 08B99AF4939C176C5EE6AD1B6378F5C4
 https://doi.org/10.3390/antibiotics10111407
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| Jezik: | Angleški jezik |
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| Vrsta gradiva: | Znanstveno delo |
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| Tipologija: | 1.01 - Izvirni znanstveni članek |
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| Organizacija: | FZV - Fakulteta za zdravstvene vede
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| Opis: | Amoxicillin (AMX) and Ciprofloxacin (CIP) are antibiotics commonly used in human medicine with high environmental toxicity and poor biodegradability. They have been found in various hospital effluents and groundwater, and their environmental impact is still not fully understood. In this work, we investigated the possibility of treating model wastewaters containing the antibiotics AMX and CIP using ozonation, with the addition of H$_2$O$_2$ under various conditions, including different pH values, H$_2$O$_2$, and ozone dosages. The quantification of and treatment efficacy for antibiotic removal were determined via solid phase extraction followed by chromatographic separation by liquid chromatography coupled with tandem triple quadrupole mass spectrometry (LC/MS/MS). This analytical system is quite efficient for the detection of all major antibiotic classes, even if they are present at very low concentrations. The efficiency of ozonation was determined by measuring the TOC (Total Organic Carbon) changes after ozonation of the model wastewater and by measuring the concentration of the two antibiotics. In a sequential activated sludge process of ozone-treated model wastewater, almost complete TOC removal and an overwhelming decrease in antibiotic concentrations (up to 99%) were observed. Ozonation resulted in complete removal of AMX and CIP in less than 30 and 120 min, respectively. The results of this work indicate that ozonation could be a suitable pretreatment method to reduce the toxicity of contaminants (AMX and CIP) and improve the biodegradability of hospital wastewater. |
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| Ključne besede: | antibiotics, amoxicillin, AMX, ciprofloxacin, CIP, hospital wastewater, hydrogen peroxide, ozone, sludge, water treatment |
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| Status publikacije: | Objavljeno |
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| Verzija publikacije: | Objavljena publikacija |
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| Poslano v recenzijo: | 30.09.2021 |
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| Datum sprejetja članka: | 10.11.2021 |
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| Datum objave: | 17.11.2021 |
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| Založnik: | MDPI |
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| Leto izida: | 2021 |
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| Št. strani: | Str. 1-13 |
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| Številčenje: | Letn. 10, št. 11, št. članka 1407 |
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| PID: | 20.500.12556/DKUM-81624  |
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| UDK: | 628.349:66.094.3-926.214:615.33 |
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| COBISS.SI-ID: | 85418243 |
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| DOI: | 10.3390/antibiotics10111407 |
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| ISSN pri članku: | 2079-6382 |
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| Datum objave v DKUM: | 06.08.2024 |
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| Število ogledov: | 228 |
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| Število prenosov: | 25 |
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| Metapodatki: |    |
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| Področja: | Ostalo
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