| Naslov: | Sex differences in motor unit behavior in patients with parkinson's disease |
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| Avtorji: | ID Nishikawa, Yuichi (Avtor)
ID Watanabe, Kohei (Avtor)
ID Holobar, Aleš (Avtor)
ID Takahashi, Tetsuya (Avtor)
ID Maeda, Noriaki (Avtor)
ID Maruyama, Hirofumi (Avtor)
ID Hyngstrom, Allison S (Avtor) |
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| Datoteke: |  Eur_J_of_Neuroscience_-_2025_-_Nishikawa_-_Sex_Differences_in_Motor_Unit_Behavior_in_Patients_With_Parkinson_s_Disease.pdf (1,38 MB)
MD5: 7CF210E147487E0285975DA66534CED1
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| Jezik: | Angleški jezik |
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| Vrsta gradiva: | Članek v reviji |
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| Tipologija: | 1.01 - Izvirni znanstveni članek |
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| Organizacija: | FERI - Fakulteta za elektrotehniko, računalništvo in informatiko
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| Opis: | The aim of this study was to determine whether there are sex differences in motor unit firing behavior in patients with Parkinson'sdisease. Twenty-seven patients with Parkinson's disease (females = 14 [age = 71.1 ± 6.8], males = 13 [age = 69.2 ± 10.3], UnifiedParkinson's Disease Rating Scale Part III score; females = 10.8 ± 4.8, males = 11.4 ± 1.4) performed a contraction at 30% of themaximal voluntary contraction. For each participant, motor unit spike trains were decomposed from high- density surface elec-tromyography data recorded from bilateral vastus lateralis muscles via blind source separation algorithms. In addition to themean discharge rates, persistent inward currents were estimated via a paired motor unit analysis. Females presented signifi-cantly greater laterality of discharge rate (p = 0.001) and persistent inward currents (p = 0.0121) than males. A significant corre-lation was observed between the discharge rate and the recruitment threshold on the bilateral side of males and the less-affectedside of females but not on the more-affected side of females. These findings indicate that sex differences in motor unit behaviorexist in Parkinson's disease patients. Motor unit behavior may be a sensitive and quantitative evaluation tool to highlight differ-ences in disease presentation between males and females. |
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| Ključne besede: | electromyography, Parkinson's diseas, sex difference, motor unit |
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| Status publikacije: | Objavljeno |
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| Verzija publikacije: | Objavljena publikacija |
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| Poslano v recenzijo: | 30.03.2025 |
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| Datum sprejetja članka: | 25.06.2025 |
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| Datum objave: | 07.07.2025 |
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| Založnik: | Wiley |
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| Leto izida: | 2025 |
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| Št. strani: | 12 str. |
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| Številčenje: | Vol. 62, iss. 1 |
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| PID: | 20.500.12556/DKUM-97549  |
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| UDK: | 616.8:004.5 |
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| COBISS.SI-ID: | 271806723 |
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| DOI: | 10.1111/ejn.70191 |
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| ISSN pri članku: | 1460-9568 |
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| Avtorske pravice: | © 2025 The Author(s) |
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| Datum objave v DKUM: | 18.03.2026 |
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| Število ogledov: | 158 |
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| Število prenosov: | 8 |
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| Metapodatki: |    |
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| Področja: | Ostalo
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