| Title: | DOLOČANJE ANTITUMORSKE AKTIVNOSTI NEKATERIH KETONUKLEOZIDOV |
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| Authors: | ID Vodenik, Tomaž (Author)
ID CENCIČ, Avrelija (Mentor) More about this mentor...  |
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| Files: |  UNI_Vodenik_Tomaz_2009.pdf (1,83 MB)
MD5: 11FB0F129F1AD2FB2D5E413942BCF060
PID: 20.500.12556/dkum/87078edc-748c-4022-b0cd-a5e7b4ef4dff
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| Language: | Slovenian |
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| Work type: | Undergraduate thesis |
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| Organization: | FKBV - Faculty of Agriculture and Life Sciences
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| Abstract: | Ugotavljali smo odzivnost oziroma rast Caco-2 celic in toksicni vpliv ketonukleozidnih derivatov ter 5-FU.
Pri testiranju smo uporabili tri razlicne ketonukleozidne substance v razlicnih koncentracijah in kontrolno 5-
FU. Ucinkovina 1,5-Di-O-4-flour-2-N4 benzoil citozin-6-troponin je delovala toksicno in zavirala rast pri
koncentracijah; 0,1 mg/mL, 0,05 mg/mL ter pri 0,025 mg/mL. Toksicno zaviralno je delovala tudi
ucinkovina 1,3-Di-O-4-flour-2-N4-benzoil citozin-6-troponin pri koncentracijah; 0,1 mg/mL, 0,05 mg/mL,
0,025mg/mL, 0,0125 mg/mL. Prav tako je zavirala kontrolna ucinkovina 5-FU rast, saj je vecina celic
propadla. |
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| Keywords: | Kljucne besede: ketonukleozidi / nukleozidni analogi / antitumorska aktivnost / Caco-2
celice / celicne kulture / gojišca |
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| Place of publishing: | Maribor |
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| Year of publishing: | 2009 |
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| PID: | 20.500.12556/DKUM-11375 |
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| NUK URN: | URN:SI:UM:DK:HY7VYW3Y |
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| Publication date in DKUM: | 01.09.2009 |
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| Views: | 2685 |
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| Downloads: | 163 |
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| Metadata: |    |
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| Categories: | FKBV
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