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Title:OBDELAVA VLAKEN Z MODIFICIRANIM KSILANOM ZA DOSEGO HEMOKOMPATIBILNIH LASTNOSTI
Authors:ID Velkova, Nena (Author)
ID Strnad, Simona (Mentor) More about this mentor... New window
ID Fras Zemljič, Lidija (Comentor)
Files:.pdf UNI_Velkova_Nena_2010.pdf (990,52 KB)
MD5: 6131374AEFEF12377B8768D575F541C9
PID: 20.500.12556/dkum/a6e95932-8241-4222-8a70-a7cc85a60adf
 
Language:Slovenian
Work type:Undergraduate thesis
Organization:FS - Faculty of Mechanical Engineering
Abstract:Razvoj hemokompatibilnih biomaterialov predstavlja izjemen izziv, saj so kardiovaskularni zapleti glavni vzrok smrti ljudi v razvitem svetu. Raziskave so zato v zadnjem času usmerjene v iskanje protitrombogenih substanc rastlinskega izvora. Cilj diplomskega dela je bil kemično modificirati ksilane različnih izvorov v smislu pridobitve protitrombogenih lastnosti ter jih aplicirati na vlaknih. Rezultati so pokazali, da je bil uporabljeni postopek sulfatacije primeren za obdelavo uporabljenih vzorcev ksilanov. Aktivirani delni tromboplastinski čas (APTT) se po sulfataciji značilno zviša v primerjavi z nesulfatiranimi vzorci. APTT se zviša z višjo vsebnostjo sulfatnih skupin v vzorcu. Po sulfatiranju postanejo ksilani topni v vodi in torej primerni za aplikacijo na vlaknih.
Keywords:hemokompatibilni biomateriali, ksilani, sulfatiranje, PET, antikoagulacijske lastnosti, titracijske metode
Place of publishing:Maribor
Publisher:[N. Velkova]
Year of publishing:2010
PID:20.500.12556/DKUM-15677 New window
UDC:677.027(043.2)
COBISS.SI-ID:14769686 New window
NUK URN:URN:SI:UM:DK:0D7D3VUI
Publication date in DKUM:17.09.2010
Views:2296
Downloads:196
Metadata:XML DC-XML DC-RDF
Categories:KTFMB - FS
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Secondary language

Language:English
Title:FIBRE TREATMENT WITH MODIFIED XYLAN FOR HEMOCOMPATIBILITY ACHIEVEMENT
Abstract:The development of hemocompatible biomaterials represents extreme challenge, as the cardiovascular complications are a main reason of deaths in developed world. For that reason, the research is focused in searching of antithrombotic substances of plant source. The main goal of study was to chemically modify xylans from different sources, to get antithrombotic properties and to apply them on fibers. The results has shown that the used procedure of sulfation was apropriate for treatment of used samples of xylans. Activated partial thromboplastin time (APTT) inceased after sulfation, compared to non sulfated samples. APTT increased with higher content of sulfated groups in the sample. After sulfation, the xylans became water soluble and as such appropriate fibre treatment.
Keywords:hemocompatible biomaterials, xylan, sulphation, PET, anticoagulation properties, titration methods


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