| Title: | Separation of parthenolide from feverfew: performance of conventional and high-pressure extraction techniques |
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| Authors: | ID Čretnik, Lucija (Author)
ID Škerget, Mojca (Author)
ID Knez, Željko (Author) |
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| Files: |  http://dx.doi.org/10.1016/j.seppur.2004.03.011
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| Language: | English |
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| Work type: | Unknown |
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| Typology: | 1.01 - Original Scientific Article |
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| Organization: | FKKT - Faculty of Chemistry and Chemical Engineering
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| Abstract: | In present work the extraction of feverfew flower heads was performed using supercritical carbon dioxide at pressures from 200 to 800 bar and at temperatures of 40, 60 and 80 °C. For comparison, the conventional extractionswith organic solvents have been performed. Dry feverfew flower heads were used as starting material. Supercritical fluid extraction (SFE) wasperformed using a semi continuous flow apparatus in a laboratory and pilot scale. The influence of process parameters on the total yield and amount of parthenolide isolated was investigated. Dynamic behaviour of the extraction runs followed by single-step separation was analysed by a mathematical model for initial constant rate extraction period and the subsequent time-dependant diffusion controlling mass transfer rate period. In order to concentrate the obtained extract in parthenolide, a two-step separation was employed. |
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| Keywords: | chemical processing, high pressure extraction, conventional extraction, supercritical CO2, parthenolide, feverfew, extraction rate, mass transfer |
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| Year of publishing: | 2005 |
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| PID: | 20.500.12556/DKUM-27206  |
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| UDC: | 66.061-987 |
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| ISSN on article: | 1383-5866 |
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| COBISS.SI-ID: | 9103894 |
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| NUK URN: | URN:SI:UM:DK:UQWQPD7S |
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| Publication date in DKUM: | 01.06.2012 |
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| Views: | 2275 |
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| Downloads: | 116 |
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| Metadata: |    |
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| Categories: | Misc.
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