| Naslov: | Stability of ranked gene lists in large microarray analysis studies |
|---|
| Avtorji: | ID Štiglic, Gregor (Avtor)
ID Kokol, Peter (Avtor) |
|---|
| Datoteke: |  Journal_of_Biomedicine_and_Biotechnology_2010_Stiglic,_Kokol_Stability_of_Ranked_Gene_Lists_in_Large_Microarray_Analysis_Studies.pdf (1,39 MB)
MD5: 8E8DA45D7193174D520C763A79CAE698
PID: 20.500.12556/dkum/d3101b42-c9de-4202-9762-a4ef279fb518
 http://www.hindawi.com/journals/bmri/2010/616358/
|
|---|
| Jezik: | Angleški jezik |
|---|
| Vrsta gradiva: | Znanstveno delo |
|---|
| Tipologija: | 1.01 - Izvirni znanstveni članek |
|---|
| Organizacija: | FZV - Fakulteta za zdravstvene vede
|
|---|
| Opis: | This paper presents an empirical study that aims to explain the relationship between the number of samples and stability of different gene selection techniques for microarray datasets. Unlike other similar studies where number of genes in a ranked gene list is variable, this study uses an alternative approach where stability is observed at different number of samples that are used for gene selection. Three different metrics of stability, including a novel metric in bioinformatics, were used to estimate the stability of the ranked gene lists. Results of this study demonstrate that the univariate selection methods produce significantly more stable ranked gene lists than themultivariate selection methods used in this study. More specifically, thousands of samples are needed for these multivariate selection methods to achieve the same level of stability any given univariate selection method can achieve with only hundreds. |
|---|
| Ključne besede: | gene selection techniques, microarray, analysis studies |
|---|
| Status publikacije: | Objavljeno |
|---|
| Verzija publikacije: | Objavljena publikacija |
|---|
| Leto izida: | 2010 |
|---|
| Št. strani: | str. 1-9 |
|---|
| Številčenje: | Letn. 2010 |
|---|
| PID: | 20.500.12556/DKUM-30841  |
|---|
| ISSN: | 1110-7243 |
|---|
| UDK: | 004.8:575 |
|---|
| COBISS.SI-ID: | 1615268 |
|---|
| DOI: | 10.1155/2010/616358 |
|---|
| ISSN pri članku: | 1110-7243 |
|---|
| NUK URN: | URN:SI:UM:DK:EJDX3NDN |
|---|
| Datum objave v DKUM: | 05.06.2012 |
|---|
| Število ogledov: | 2234 |
|---|
| Število prenosov: | 404 |
|---|
| Metapodatki: |    |
|---|
| Področja: | Ostalo
|
|---|
|
:
|
Kopiraj citat |
|---|
| | | | Skupna ocena: | (0 glasov) |
|---|
| Vaša ocena: | Ocenjevanje je dovoljeno samo prijavljenim uporabnikom. |
|---|
| Objavi na: |  |
|---|
Postavite miškin kazalec na naslov za izpis povzetka. Klik na naslov izpiše
podrobnosti ali sproži prenos. |
