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Title:Usefulness of follicular fluid estradiol and progesterone concentration measurement in predicting outcome of IVF/ICSI natural cycles
Authors:ID Gavrić-Lovrec, Vida (Author)
ID Vlaisavljević, Veljko (Author)
ID Kovačič, Borut (Author)
ID Gorenjak, Maksimiljan (Author)
ID Reljič, Milan (Author)
Files:URL http://www.actamedbio.mf.uni-mb.si/article/Uporabnost+merjenja+koncentracije+estradiola+in+progesterona+v+folikularni+teko%C4%8Dini+pri+napovedovanju+izida+IVFICSI+postopka+v+naravnem+ciklusu._408
 
URL http://www.actamedbio.mf.uni-mb.si/article/Uporabnost+merjenja+koncentracije+estradiola+in+progesterona+v+folikularni+teko%C4%8Dini+pri+napovedovanju+izida+IVFICSI+postopka+v+naravnem+ciklusu._408
 
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MD5: 4AB100BABB85209A68CB6D42CFC032E4
 
Language:English
Work type:Scientific work
Typology:1.01 - Original Scientific Article
Organization:MF - Faculty of Medicine
Abstract:Purpose: The aim of the study was to establish whether follicular fluid (FF) estradiol (E2) and progesterone (P) measurement could be used to predict the outcome of unstimulated IVF/ICSI cycles. Methods: 91 women underwent 150 unstimulated IVF/ICSI cycles (78 IVF and 72 ICSI). Follicular fluid samples were collected at the time of oocyte recovery. Using the ttest, FF E2 and FF P levels and their ratios (FF P/FF E2) were compared between cycles with successful (with oocyte) and unsuccessful (without oocyte) oocyte recovery, between cycles with and without fertilization and between nonconception and conception cycles. Results: The oocyte recovery rate was 86.7% (123/150), the fertilization rate 68.3% (84/123) and the pregnancy rate per oocyte recovery 14.0% (21/150). The average FF E2 level was 3530 +/- 1339 nmol/L, average FF P 20649 +/- 9489 nmol/Land average FF P/FF E2 ratio 7.18 +/- 6.42. There were no statistically significant differences in FF E2, FF P levels and their ratio between cycles with unsuccessful and successful oocyte recovery, between cycles without and with fertilization, and between nonconception and conception cycles. Conclusion: From the FF E2 and P levels and their ratio, it is not possible to make inferences to the likelihood of oocyte recovery, fertilization and conception in unstimulated IVF/ICSI cycles.
Keywords:folikularna tekočina, naravni ciklus, estradiol, progesteron, IVF/ICSI izhod
Publication status:Published
Publication version:Version of Record
Publication date:01.01.2012
Year of publishing:2012
Number of pages:str. 39-45
Numbering:Letn. 5, št. 1
PID:20.500.12556/DKUM-49634-b3ce69c9-1100-cab8-20c6-96524fa162f1 New window
UDC:618.177-089.888.11
ISSN on article:1855-5640
COBISS.SI-ID:4331327 New window
NUK URN:URN:SI:UM:DK:ZG2TNZIU
Publication date in DKUM:10.07.2015
Views:1634
Downloads:91
Metadata:XML DC-XML DC-RDF
Categories:Misc.
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Record is a part of a journal

Title:Acta medico-biotechnica : AMB
Publisher:Medicinska fakulteta, Medicinska fakulteta, Univerzitetna založba Univerze v Mariboru
ISSN:1855-5640
COBISS.SI-ID:242526720 New window

Secondary language

Language:Slovenian
Title:Uporabnost merjenja koncentracije estradiola in progesterona v folikularni tekočini pri napovedovanju izida IVF/ICSI postopka v naravnem ciklusu
Abstract:Namen: Namen raziskave je bil ugotoviti ali lahko na osnovi koncentracije estradiola (E2) in progesterona (P) ter njunega razmerja v folikularni tekočini predvidimo izhod IVF/ICSI postopkov v naravnih ciklusih. Metode: V raziskavo smo vključili 91 žensk, pri katerih smo naredili 150 postopkov IVF/ICSI (78 IVF in 72 ICSI) v naravnem ciklusu. Folikularno tekočino smo zbrali pri aspiraciji foliklov. S t-testom testom smo primerjali koncentracije E2 in P v folikularni tekočini (FT) in njuno razmerje (FT P/FT E2) med ciklusi z uspešno (z jajčno celico) in ciklusi z neuspešno (brez jajčne celice) aspiracijo foliklov, med ciklusi z oploditvijo in ciklusi brez oploditve jajčne celice in med ciklusi z zanositvijo in ciklusi brez zanositve. Rezultati: Jajčno celico smo dobili v 123 (86,7 %) ciklusih, do oploditve je prišlo v 84 (68,3 %) in zanositve v 21 ciklusih (delež zanositve na ciklus 14,0 %). Povprečna koncentracija E2 v FT je bila 3530 +/- 1339 nmol/L, povprečna koncentracija P v FT 20649 +/- 9489 nmol/L in povprečna vrednost razmerja FT P/FT E2 7,18 +/- 6,42. Povprečne vrednost E2, P in njunega razmerja v FT se niso statistično pomembno razlikovale med ciklusi z uspešno in neuspešno aspiracijo jajčnih foliklov, med ciklusi z in brez oploditve jajčne celice in med ciklusi z in brez zanositve. Zaključek: Na osnovi vrednosti E2 in P v folikularni tekočini ne moremo predvideti uspešnosti postopkov IVF/ICSI v naravnem ciklusu.
Keywords:follicular fluid, natural cycle, estradiol, progesterone, IVF/ICSI outcome


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  1. Acta medico-biotechnica

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