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Title:Dinamika cerebralne oksigenacije pri hiperventilaciji in hipoventilaciji
Authors:ID Rotman, Eva (Author)
ID Križmarić, Miljenko (Mentor) More about this mentor... New window
ID Dolenšek, Jurij (Comentor)
Files:.pdf VS_Rotman_Eva_2017.pdf (1,40 MB)
MD5: 83CF60DF0F6BC5526786498AC2B4F21A
PID: 20.500.12556/dkum/5676263f-fed4-4e25-a0b6-01a7cfd6e5e1
 
Language:Slovenian
Work type:Bachelor thesis/paper
Typology:2.11 - Undergraduate Thesis
Organization:FZV - Faculty of Health Sciences
Abstract:Uvod: Možgani za svoje delovanje potrebujejo stalen dotok krvi. V določenih kliničnih situacijah pa je potrebno zmanjšati pretok krvi, ob tem je nujno spremljanje količin kisika. Z raziskavo smo želeli ugotoviti, ali se lahko s tehniko bližnje infrardeče spektroskopije zazna spremembe kisika v možganih pri kratkotrajni hiperventilaciji in hipoventilaciji. Metode: V teoretičnem delu smo pridobili podatke z deskriptivno metodo dela, v empiričnem pa smo uporabili kvantitativno metodo z namenskim vzorcem. Regionalno nasičenost kisika v možganih smo izmerili s spektroskopijo v bližnjem infrardečem polju. Med preizkusom hiperventilacije in hipoventilacije smo spremljali vrednosti dihanja, pulza, PETCO2 in SpO2. Rezultati: V času hiperventilacije so se vrednosti rSO2 znižale za 2 % v primerjavi z začetnimi vrednostmi. Padanje se je nadaljevalo v času počitka 1, kljub temu, da se je PETCO2 zviševal. V času hipoventilacije počitka 3 smo opazili ponovno zviševanje rSO2 parametra. Diskusija in zaključek: S testom hiperventilacije in hipoventilacije smo prikazali vpliv PETCO2 na spreminjanje rSO2. Glavni mehanizem, ki je odgovoren za zmanjšanje rSO2 pri hiperventilaciji, je hipokapnija.
Keywords:Možganska prekrvavitev, avtoregulacija, hipokapnija, vazokonstrikcija, spektroskopija v bližnjem infrardečem polju.
Place of publishing:Maribor
Publisher:[E. Rotman]
Year of publishing:2017
PID:20.500.12556/DKUM-67385 New window
UDC:616.8(043.2)
COBISS.SI-ID:2352292 New window
NUK URN:URN:SI:UM:DK:BTXPESKC
Publication date in DKUM:13.09.2017
Views:2009
Downloads:165
Metadata:XML DC-XML DC-RDF
Categories:FZV
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Licences

License:CC BY-NC-ND 4.0, Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
Link:http://creativecommons.org/licenses/by-nc-nd/4.0/
Description:The most restrictive Creative Commons license. This only allows people to download and share the work for no commercial gain and for no other purposes.
Licensing start date:16.08.2017

Secondary language

Language:English
Title:Dynamics of cerebral oxygenation when performing hyperventilation and hypoventilation
Abstract:Introduction: Our brain require constant supply of blood for its functioning. But in some clinical situations it is indispensable to reduce blood flow. In these cases it is necessary to monitor the oxygen level in the brain. With the research we wanted to find out wheter near-infrared spectroscopy detects changes of oxygen in brain during short term hyperventilation and hypoventilation. Methods: In the theoretical part we obtained data with the descriptive method whereas in the empirical part we used a quantitative method with a purposive sample. The regional oxygen saturation in the brain was measured with near-infrared spectroscopy. We monitored values of respiration, pulse, PETCO2 and SpO2 during the test of hyperventilation and hypoventilation. Results: In hyperventilation the rSO2 values were decreased by 2 % from the baseline. The decline continued through the 1st rest despite the elevating PETCO2. In hypoventilation and the 3rd period of rest that we noticed an increase of rSO2 parameters. Discussion: The hyperventilation and hypoventilation test showed the effect of PETCO2 on the alteration of rSO2 parameter. The main mechanism, responsible for the decrease of rSO2 in hyperventilation is hypocapnia.
Keywords:Cerebral blood flow, autoregulation, hypocapnia, vasoconstiction, near-infrared spectroscopy.


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