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Title:Polyurethanes for medical use
Authors:ID Pivec, Tanja (Author)
ID Sfiligoj-Smole, Majda (Author)
ID Gašparič, Petra (Author)
ID Stana-Kleinschek, Karin (Author)
Files:.pdf TEKSTILEC_2017_Pivec_et_al._Polyurethanes_for_Medical_Use.pdf (383,90 KB)
MD5: 798AC0D2B9139E236F276844DEF0660E
PID: 20.500.12556/dkum/e135dec6-4296-449a-b602-1ebe87999874
 
URL http://www.tekstilec.si/wp-content/uploads/2017/09/182-197.pdf
 
Language:English
Work type:Scientific work
Typology:1.02 - Review Article
Organization:FS - Faculty of Mechanical Engineering
Abstract:Polyurethanes are synthetic copolymers containing urethane linkages in their complex chemical structure. They consist of three monomers: a diisocyanate, a polyol and a chain extender, which enables the synthesis of an endless number of polyurethanes with different physicochemical and mechanical properties. The physicochemical properties of various polyurethanes are largely dependent on the conformation of polyols, which may contain two or more different polyols, stabilisers, catalysts, liquids or solid additives and, in the case of foams, foaming agents. Depending on the structure of the polyols, i.e. the length of the chain, structure of the units (aliphatic or aromatic), ester or ether groups, or functionalisation by hydroxyl groups, polyurethanes may be flexible or rigid, and therefore suitable for various applications. In addition to the physical and chemical structure of polyurethanes, this review paper specifically addresses their use in medicine, particularly in wound dressings, tissue engineering scaffolds and drug delivery with nanoparticles and nanocapsules, and provides guidelines for the development of new biodegradable polyurethane materials.
Keywords:segmented polyurethanes, chemical structure, reactants, medical applications
Publication status:Published
Publication version:Version of Record
Year of publishing:2017
Number of pages:str. 182-197
Numbering:Letn. 60, št. 3
PID:20.500.12556/DKUM-68637 New window
ISSN:0351-3386
UDC:677.494.675
ISSN on article:0351-3386
COBISS.SI-ID:20726294 New window
DOI:10.14502/Tekstilec2017.60.182-197 New window
NUK URN:URN:SI:UM:DK:FJUKFBGZ
Publication date in DKUM:03.10.2017
Views:1957
Downloads:581
Metadata:XML DC-XML DC-RDF
Categories:Misc.
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Record is a part of a journal

Title:Tekstilec. glasilo slovenskih tekstilcev
Shortened title:Tekstilec
Publisher:Zveza inženirjev in tehnikov tekstilcev, Splošno združenje tekstilne industrije, Zveza inženirjev in tehnikov tekstilcev, Splošno združenje tekstilne industrije, Društvo inženirjev in tehnikov tekstilcev, Univerza v Ljubljani, Naravoslovnotehniška fakulteta, Oddelek za tekstilstvo, Založba Univerze v Ljubljani
ISSN:0351-3386
COBISS.SI-ID:763396 New window

Licences

License:CC BY 4.0, Creative Commons Attribution 4.0 International
Link:http://creativecommons.org/licenses/by/4.0/
Description:This is the standard Creative Commons license that gives others maximum freedom to do what they want with the work as long as they credit the author.
Licensing start date:03.10.2017

Secondary language

Language:Slovenian
Title:Poliuretani za medicinsko uporabo
Abstract:Poliuretani so v svoji kompleksni kemijski zgradbi sintetični kopolimeri z uretansko vezjo. Njihova sestava iz treh različnih monomernih enot: diizocianatov, poliolov in podaljševalcev verig, omogoča sintezo neomejenega števila poliuretanov z različnimi fizikalno-kemijskimi in mehanskimi lastnostmi. Fizikalno-kemijske lastnosti različnih poliuretanov so odvisne predvsem od konformacije poliolov, ki lahko vsebujejo dva ali več različnih poliolov, stabilizatorjev, katalizatorjev, tekočih ali trdnih aditivov in pri penah tudi penilcev. Poliuretani so lahko fleksibilni ali togi in tako uporabni za različne namembnosti, kar je odvisno od dolžine molekul, alifatske ali aromatske strukture poliolov, prisotnosti estrskih ali eterskih skupin in funkcionalizacije poliolov s hidroksilnimi skupinami. Pregledni znanstveni članek poleg fizikalne in kemijske strukture poliuretanov posebej obravnava njihovo uporabo v medicini, zlasti pri obližih za rane, tekstilijah za tkivno inženirstvo, materialih s kontroliranim sproščanjem zdravilnih učinkovin, nanodelcih ali nanokapsulah, in podaja smernice za razvoj novih biološko razgradljivih poliuretanskih materialov.
Keywords:segmentirani poliuretani, kemijska struktura, reaktanti, medicinska uporaba


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