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Title:Primerjava stranskih učinkov 7 in 14 dnevnega zdravljenja okužbe s helicobacter pylori
Authors:ID Ojsteršek, Tjaša (Author)
ID Tomažič, Jožefa (Mentor) More about this mentor... New window
Files:.pdf VS_Ojstersek_Tjasa_2020.pdf (657,47 KB)
MD5: 6AEA0121A5952E00202214347BCCC958
PID: 20.500.12556/dkum/1693f6e2-b794-4413-95da-70ea27125e23
 
Language:Slovenian
Work type:Bachelor thesis/paper
Typology:2.11 - Undergraduate Thesis
Organization:FZV - Faculty of Health Sciences
Abstract:Izhodišča: Helicobacter pylori okužba je najpogostejša kronična bakterijska okužba pri ljudeh. Namen zaključnega dela je bil ugotoviti razlike v stranskih učinkih zdravljenja okužbe s Helicobacter pylori med 7 dnevno in 14 dnevno shemo zdravljenja. Raziskovalna metodologija in metode: Uporabljena je bila deskriptivna in kvantitativna metodologija. Za raziskovalni del smo pridobili podatke s pomočjo anonimnega anketnega vprašalnika. Pridobljene podatke smo grafično predstavili s programom Microsoft Excel in prikazali s programom Microsoft Word. V raziskavi je sodelovalo 100 odraslih bolnikov, ki so imeli potrjeno okužbo s Helicobacter pylori. Na podlagi analize pridobljenih podatkov smo ugotovili vrsto in pogostnost stranskih učinkov 14 dnevnega zdravljenja okužbe in jih primerjali s podatki o sopojavih 7 dnevnega zdravljenja, ki so bili ugotovljeni v istem diagnostičnem centru in že objavljeni. Rezultati: Stranski učinki so primerljivi med 7 in 14 dnevnim zdravljenjem in se kljub podaljšanju zdravljenja ne spreminjajo glede vrste oziroma pogostnosti. Prisotni so pri 25,2 % 7 dnevnega zdravljenja in pri 26% 14 dnevnega zdravljenja. Najpogostejši stranski učinki zdravljenja so bili kovinski občutek v ustih, slabost, diareja in bolečine v trebuhu. Nihče od anketiranih zaradi stranski učinkov ni bil hospitaliziran. Diskusija in zaključek: Podatki iz raziskave nam povedo, da sta 7 in 14 dnevna shema zdravljenja glede pogostnosti stranskih učinkov primerljivi. Statistično značilnega povečanja števila stranskih učinkov oziroma zapletov pri podaljšanju zdravljenja ni bilo zaznati.
Keywords:Helicobacter pylori, stranski učinki zdravljenja, antibiotiki, sheme eradikacijske terapije, bolnik, zdravstvena vzgoja
Place of publishing:Maribor
Publisher:[T. Ojsteršek]
Year of publishing:2020
PID:20.500.12556/DKUM-77308 New window
UDC:579.84:616.34-08(043.2)
COBISS.SI-ID:28653827 New window
NUK URN:URN:SI:UM:DK:WFF0M99E
Publication date in DKUM:21.09.2020
Views:1454
Downloads:146
Metadata:XML DC-XML DC-RDF
Categories:FZV
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Licences

License:CC BY-NC-ND 4.0, Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
Link:http://creativecommons.org/licenses/by-nc-nd/4.0/
Description:The most restrictive Creative Commons license. This only allows people to download and share the work for no commercial gain and for no other purposes.
Licensing start date:26.08.2020

Secondary language

Language:English
Title:Comparison of side effects at 7 and 14 days treatment for helicobacter pylori infection
Abstract:Introduction: Helicobacter pylori is the most prevalent chronic bacterial infection in humans. The purpose of the concluding word was to identify the difference in side effects of 7 and 14 day antimicrobial therapy for Helicobacter pylori infection. We included 100 adult patients who were treated with 14 day antimicrobial therapy. This data were compared to side effects data of 7 day antimicrobial therapy collected by the same method in the same center, that has already been published. Research methods: We used descriptive and quantitative methodology in our work. Data were obtained for the research part using an anonymous questionnaire. The obtained data were graphically presented with Microsoft Excel and displayed with Microsoft Word. Results: Based on the analysis od the obtained data, we found that similar side effects were present in patients treated with 7-day or 14-day antimicrobial regimens. Side effects did not differ between 7 and 14 day therapies in type or grade of side effects. They were present in 25,2 % of patients on 7 day treatment and in 26% of those on 14 day treatment.. The most common side effects of the treatmed were metallic taste in the mouth, nausea, diarrhea and abdominal pain. None of the patients were hospitalized due to side effects. Discussion and concclusion: Data obtained from surveys tell us that side effects of 7- and 14-day treatment regimens are comparable. There is no statistically significant increase in the number of side effects or complications in 14 day therapies compared to 7 day therapies.
Keywords:Helicobacter pylori, treatment side effects, antibiotics, eradication therapy schemes, patient, health education


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