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Title:Povezava vrednosti selena v amnijski tekočini z zastojem plodove rasti in kromosomskimi napakami ploda
Authors:ID Ogrizek - Pelkič, Ksenija (Author)
ID Takač, Iztok (Mentor) More about this mentor... New window
Files:.pdf DOK_Ogrizek_-_Pelkic_Ksenija_2021.pdf (1,19 MB)
MD5: A627F58C5E97A3EACCB40D82469D438C
PID: 20.500.12556/dkum/14aedece-a068-4355-ac4d-339e7023b222
 
Language:Slovenian
Work type:Doctoral dissertation
Typology:2.08 - Doctoral Dissertation
Organization:MF - Faculty of Medicine
Abstract:Cilj raziskave je bil ovrednotiti vlogo vrednosti selena v amnijski tekočini, da bi razumeli njegovo možno vlogo pri razvoju SGA in pojavnostjo kromosomskih napak ploda.Vrednosti selena smo izmerili v 327 vzorcih plodovnice. Med 310 živorojenimi novorojenci je bilo 267 (86,1 %) otrok, ki so odgovarjali po teži gestacijski starosti (AGA), pri 43 (13,8 %) pa smo ob rojstvu ocenili, da je otrok premajhen za gestacijsko starost (SGA). Pri 17 (5,2 %) preiskovankah smo ugotovili nepravilen citogenetski izvid pri plodu. Vrednosti selena v amnijski tekočini v skupini s SGA novorojenci so bile statistično značilno nižje kot v skupini z AGA (4,8 ± 1,9 µg/L napram 5,6 ± 2,5 µg/L (p = 0,017). Razmerje obetov 0.859 kaže, da se je pri višjih vrednostih selena v amnijski tekočini verjetnost rojstva otroka s SGA manjša Srednja vrednost in standardni odklon vrednosti selena v amnijski tekočini pri plodovih s kromosomskimi nepravilnostmi je bila 5,5 ± 2,3 µg/L.
Keywords:Selen, amnijska tekočina, novorojenec s premajhno težo za gestacijsko starost, kromosomske napake ploda
Place of publishing:Maribor
Year of publishing:2021
PID:20.500.12556/DKUM-78770 New window
COBISS.SI-ID:86247171 New window
NUK URN:URN:SI:UM:DK:XBQUINZQ
Publication date in DKUM:24.11.2021
Views:1029
Downloads:93
Metadata:XML DC-XML DC-RDF
Categories:MF
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Licences

License:CC BY-NC-ND 4.0, Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
Link:http://creativecommons.org/licenses/by-nc-nd/4.0/
Description:The most restrictive Creative Commons license. This only allows people to download and share the work for no commercial gain and for no other purposes.
Licensing start date:24.02.2021

Secondary language

Language:English
Title:Association of selenium levels in amniotic fluid correlate with Small-For-Gestational Age Newborns and chromosomal abnormalities in the fetus
Abstract:This prospective, single center study investigated the relationships between selenium concentrations in amniotic fluid and pregnancy outcomes. 327 samples of amniotic fluid were evaluated.The number of normal live newborns was 310, 267 (86.1%) newborns were assigned as appropriate for gestational age (AGA) and 43 (13.8%) newborns were diagnosed small for gestational age (SGA). Patients with SGA newborns had significantly lower mean values of amniotic fluid concentrations of selenium compared to AGA newborns (4.8 ± 1.9 µg/L versus 5.6 ± 2.5 µg/L (p = 0.017). In 17 (5.2 %) cases, chromosomal abnormalities were found. Mean values of selenium concentrations in cases with chromosomal abnormalities were 5.5 ± 2.3 µg/L.
Keywords:Selenium, amniotic fluid, small for gestational age newborns, chromosomalities in the fetus


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