Intervencije za izboljšanje oksigenacije kritično bolnih s COVID-19

Špalir-Kujavec, Betka

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Title:	Intervencije za izboljšanje oksigenacije kritično bolnih s COVID-19
Authors:	ID Špalir-Kujavec, Betka (Author) ID Dobnik, Mojca (Mentor) More about this mentor... ID Halec, Bine (Comentor)
Files:	MAG_Spalir-Kujavec_Betka_2023.pdf (909,78 KB) MD5: F645DCA3A170A1A82A5B4FDBB0CA0378
Language:	Slovenian
Work type:	Master's thesis/paper
Typology:	2.09 - Master's Thesis
Organization:	FZV - Faculty of Health Sciences
Abstract:	Uvod: Koronavirusna bolezen 2019 pri kritično bolnih povzroča hudo obliko akutnega respiratornega distresnega sindroma. Zadostna oksigenacija je za preživetje teh pacientov ključnega pomena. Ker invazivna mehanska ventilacija za zagotavljanje zadostne oksigenacije v večini primerov ne zadostuje, želimo z zaključnim delom predstaviti tri najpogosteje uporabljene intervencije za izboljšanje oksigenacije pri kritično bolnih s koronavirusno boleznijo 2019 ter jih medsebojno primerjati. Metode: Uporabili smo deskriptivno-opisno metodo delo. Izvedli smo pregled z analizo in sintezo znanstvene in strokovne literature. Literaturo smo pregledali v mednarodnih podatkovnih bazah Cochrane Library, PubMed, Wiley Online Library in ScienceDirect. Iskanje literature z vključitvijo in izključitvijo smo prikazali po priporočilih PRISMA. Članke smo kritično ocenili, razvrstili po hierarhiji dokazov in predstavili v obliki tabele. Rezultati: V končno analizo smo vključili 16 člankov. Našli smo osem raziskav na temo pronacije, tri raziskave na temo bronhoskopije ter pet raziskav na temo inhalacijski dušikov oksid. Ugotovili smo, da je pronacija izmed izpostavljenih intervencij za izboljšanje oksigenacije kritično bolnih s koronavirusno boleznijo 2019 najpogosteje uporabljena in najbolj učinkovita. Kombinacija intervencij za izboljšanje oksigenacije se je izkazala kot reševalno zdravljenje pri kritično bolnih s koronavirusno boleznijo 2019 s hudo obliko akutnega respiratornega distresnega sindroma. Razprava in zaključek: Pronacija je za izboljšanje oksigenacije in hitrejše okrevanje najučinkovitejša. Bronhoskopija je izmed izpostavljenih intervencij najmanj raziskana.
Keywords:	pacienti s koronavirusno boleznijo 2019, oksigenacija, bronhoskopija, pronacija, dušikov oksid
Place of publishing:	Maribor
Publisher:	[B. Špalir Kujavec]
Year of publishing:	2023
PID:	20.500.12556/DKUM-83737
UDC:	616.98-085:578.834(043.2)
COBISS.SI-ID:	145587971
Publication date in DKUM:	27.03.2023
Views:	912
Downloads:	174
Metadata:
Categories:	FZV
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Licences

License:	CC BY-NC-ND 4.0, Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International

Link:	http://creativecommons.org/licenses/by-nc-nd/4.0/
Description:	The most restrictive Creative Commons license. This only allows people to download and share the work for no commercial gain and for no other purposes.
Licensing start date:	27.01.2023

Secondary language

Language:	English
Title:	Interventions to improve oxygenation of critically ill patients with COVID-19
Abstract:	Introduction: The coronavirus disease 2019 causes a severe form of acute respiratory distress syndrome in critically ill patients. Adequate oxygenation is critical to the survival of these patients. Since invasive mechanical ventilation is not sufficient to ensure adequate oxygenation in most cases, we present and compare the three most commonly used interventions for the improvement of oxygenation in critically ill patients with the coronavirus disease 2019. Methods: Descriptive method was used. A review with analysis and synthesis of scientific and professional literature was carried out. We reviewed the literature in the international databases Cochrane Library, PubMed, Wiley Online Library, and ScienceDirect. A literature search with inclusion and exclusion was performed according to PRISMA recommendations. We critically evaluated the articles, classified them according to the hierarchy of evidence and presented them in the form of a table. Results: 16 articles were included in the final analysis. We found eight studies on the topic of pronation, three studies on the topic of bronchoscopy, and five studies on the topic of inhaled nitric oxide. Pronation was found to be the most frequently used and most effective among exposed interventions for improving oxygenation of critically ill patients with coronavirus disease 2019. A combination of interventions to improve oxygenation has shown to be a life-saving treatment for critically ill COVID-19 patients with severe acute respiratory distress syndrome. Discussion and conclusion: Pronation is the most effective intervention for improving oxygenation and speeding recovery. Bronchoscopy is the least studied intervention of the exposed interventions.
Keywords:	patients with coronavirus disease 2019, oxygenation, bronchoscopy, prone position, nitric oxide

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