| Title: | Antimicrobial resistance of Acetobacter and Komagataeibacter species originating from vinegars |
|---|
| Authors: | ID Cepec, Eva (Author)
ID Trček, Janja (Author) |
|---|
| Files: |  Antimicrobial_Resistance_of_Acetoba-Cepec-2022.pdf (444,89 KB)
MD5: FF7E5E090A49412237C83DBB2DD30E99
 https://www.mdpi.com/1660-4601/19/1/463
|
|---|
| Language: | English |
|---|
| Work type: | Article |
|---|
| Typology: | 1.01 - Original Scientific Article |
|---|
| Organization: | FNM - Faculty of Natural Sciences and Mathematics
FKKT - Faculty of Chemistry and Chemical Engineering
|
|---|
| Abstract: | Consumers’ preference towards healthy and novel foods dictates the production of organic unfiltered bottled vinegar that still contains acetic acid bacteria. After ingesting vinegar, the bacteria come into close contact with the human microbiota, creating the possibility of horizontal gene transfer, including genetic determinants for antibiotic resistance. Due to the global spread of antimicrobial resistance (AMR), we analyzed the AMR of Acetobacter and Komagataeibacter species originating mainly from vinegars. Six antibiotics from different structural groups and mechanisms of action were selected for testing. The AMR was assessed with the disk diffusion method using various growth media. Although the number of resistant strains differed among the growth media, 97.4%, 74.4%, 56.4%, and 33.3% of strains were resistant to trimethoprim, erythromycin, ciprofloxacin, and chloramphenicol, respectively, on all three media. Moreover, 17.9% and 53.8% of all strains were resistant to four and three antibiotics of different antimicrobial classes, respectively. We then looked for antimicrobial resistance genes in the genome sequences of the reference strains. The most common genetic determinant potentially involved in AMR encodes an efflux pump. Since these genes pass through the gastrointestinal tract and may be transferred to human microbiota, further experiments are needed to analyze the probability of this scenario in more detail. |
|---|
| Keywords: | acetic acid bacteria, Acetobacter, Komagataeibacter, antimicrobial resistance, trimethoprim resistance, erythromycin resistance, ciprofloxacin resistance, chloramphenicol resistance, ampicillin resistance, gentamicin resistance |
|---|
| Publication status: | Published |
|---|
| Publication version: | Version of Record |
|---|
| Submitted for review: | 04.12.2021 |
|---|
| Article acceptance date: | 30.12.2021 |
|---|
| Publication date: | 01.01.2022 |
|---|
| Publisher: | MDPI |
|---|
| Year of publishing: | 2022 |
|---|
| Number of pages: | str. 1-10 |
|---|
| Numbering: | Letn. 19, Št. 1 |
|---|
| PID: | 20.500.12556/DKUM-85273  |
|---|
| UDC: | 579 |
|---|
| ISSN on article: | 1660-4601 |
|---|
| COBISS.SI-ID: | 91776259 |
|---|
| DOI: | 10.3390/ijerph19010463 |
|---|
| Publication date in DKUM: | 24.08.2023 |
|---|
| Views: | 651 |
|---|
| Downloads: | 92 |
|---|
| Metadata: |    |
|---|
| Categories: | Misc.
|
|---|
|
:
|
Copy citation |
|---|
| | | | Average score: | (0 votes) |
|---|
| Your score: | Voting is allowed only for logged in users. |
|---|
| Share: |  |
|---|
Hover the mouse pointer over a document title to show the abstract or click
on the title to get all document metadata. |
