| Title: | Urinary metabolic biomarker profiling for cancer diagnosis by terahertz spectroscopy : review and perspective |
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| Authors: | ID Abina, Andreja (Author)
ID Korošec, Tjaša (Author)
ID Puc, Uroš (Author)
ID Jazbinšek, Mojca (Author)
ID Zidanšek, Aleksander (Author) |
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| Files: |  Abina-2023-Urinary_Metabolic_Biomarker_Profili.pdf (12,51 MB)
MD5: 4EB2C464969F02A1562A76FDDFA6AAD0
 https://doi.org/10.3390/photonics10091051
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| Language: | English |
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| Work type: | Scientific work |
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| Typology: | 1.02 - Review Article |
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| Organization: | FNM - Faculty of Natural Sciences and Mathematics
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| Abstract: | In the last decade, terahertz (THz) technologies have been introduced to the detection, identification, and quantification of biomolecules in various biological samples. This review focuses on substances that represent important biomarkers in the urine associated with various cancers and their treatments. From a diagnostic point of view, urine liquid biopsy is particularly important because it allows the non-invasive and rapid collection of large volumes of samples. In this review, the THz spectral responses of substances considered metabolic biomarkers in urine and obtained in previous studies are collected. In addition, the findings from the relatively small number of prior studies that have already been carried out on urine samples are summarised. In this context, we also present the different THz methods used for urine analysis. Finally, a brief discussion is given, presenting perspectives for future research in this field, interpreted based on the results of previous studies. This work provides important information on the further application of THz techniques in biomedicine for detecting and monitoring urinary biomarkers for various diseases, including cancer. |
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| Keywords: | terahertz spectroscopy, urinary biomarkers, metabolic biomarkers, cancer diagnostics, biomolecules, non-invasive detection, biomedical detection |
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| Publication status: | Published |
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| Publication version: | Version of Record |
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| Submitted for review: | 31.07.2023 |
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| Article acceptance date: | 12.09.2023 |
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| Publication date: | 15.09.2023 |
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| Publisher: | MDPI |
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| Year of publishing: | 2023 |
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| Number of pages: | Str. 1-36 |
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| Numbering: | Letn. 10, Št. 9, št. članka 1051 |
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| PID: | 20.500.12556/DKUM-87383  |
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| UDC: | 577 |
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| ISSN on article: | 2304-6732 |
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| COBISS.SI-ID: | 164724483 |
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| DOI: | doi.org/10.3390/photonics10091051 |
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| Publication date in DKUM: | 14.03.2024 |
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| Views: | 324 |
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| Downloads: | 51 |
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| Metadata: |    |
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| Categories: | Misc.
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