| Title: | Sustainable Biodegradable Biopolymer-Based Nanoparticles for Healthcare Applications |
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| Authors: | ID Kučuk, Nika (Author)
ID Primožič, Mateja (Author)
ID Knez, Željko (Author)
ID Leitgeb, Maja (Author) |
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| Files: |  Kucuk-2023-Sustainable_Biodegradable_Biopolyme.pdf (3,50 MB)
MD5: FEC57D105A7A9B0CB9160DA53E19842D
 https://www.mdpi.com/1422-0067/24/4/3188
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| Language: | English |
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| Work type: | Article |
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| Typology: | 1.02 - Review Article |
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| Organization: | FKKT - Faculty of Chemistry and Chemical Engineering
MF - Faculty of Medicine
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| Abstract: | Biopolymeric nanoparticles are gaining importance as nanocarriers for various biomedical applications, enabling long-term and controlled release at the target site. Since they are promising delivery systems for various therapeutic agents and offer advantageous properties such as biodegradability, biocompatibility, non-toxicity, and stability compared to various toxic metal nanoparticles, we decided to provide an overview on this topic. Therefore, the review focuses on the use of biopolymeric nanoparticles of animal, plant, algal, fungal, and bacterial origin as a sustainable material for potential use as drug delivery systems. A particular focus is on the encapsulation of many different therapeutic agents categorized as bioactive compounds, drugs, antibiotics, and other antimicrobial agents, extracts, and essential oils into protein- and polysaccharide-based nanocarriers. These show promising benefits for human health, especially for successful antimicrobial and anticancer activity. The review article, divided into protein-based and polysaccharide-based biopolymeric nanoparticles and further according to the origin of the biopolymer, enables the reader to select the appropriate biopolymeric nanoparticles more easily for the incorporation of the desired component. The latest research results from the last five years in the field of the successful production of biopolymeric nanoparticles loaded with various therapeutic agents for healthcare applications are included in this review. |
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| Keywords: | nanoparticles, biopolymers, therapeutic substances, incorporation, biocompatibility, healthcare, biomedical applications |
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| Publication status: | Published |
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| Publication version: | Version of Record |
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| Submitted for review: | 29.12.2022 |
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| Article acceptance date: | 02.02.2023 |
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| Publication date: | 06.02.2023 |
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| Publisher: | MDPI |
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| Year of publishing: | 2023 |
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| Number of pages: | Str. 1-45 |
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| Numbering: | Letn. 24, Št. 4, št. članka 3188 |
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| PID: | 20.500.12556/DKUM-87944  |
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| UDC: | 577:620.3 |
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| ISSN on article: | 1422-0067 |
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| COBISS.SI-ID: | 140882435 |
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| DOI: | 10.3390/ijms24043188 |
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| Publication date in DKUM: | 02.04.2024 |
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| Views: | 411 |
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| Downloads: | 38 |
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| Metadata: |    |
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| Categories: | Misc.
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