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Title:
Potential interactions between cannabinoids and estrogens in common diseases
Authors:
ID
Hojnik, Marko
(
Author
)
ID
Dobovišek, Luka
(
Author
)
ID
Ferk, Polonca
(
Author
)
Files:
http://www.actamedbio.mf.uni-mb.si/13id_amb_110_14.pdf
07.pdf
(131,65 KB)
MD5: EB1B44F32C2A94C4C4A5E9A2BFAAC61D
Language:
English
Work type:
Scientific work
Typology:
1.02 - Review Article
Organization:
MF - Faculty of Medicine
Keywords:
estrogeni
,
kanabinoidi
,
osteoporoza
,
ateroskleroza
,
rak
Publication status:
Published
Publication version:
Version of Record
Publication date:
01.01.2014
Year of publishing:
2014
Number of pages:
str. 23-29
Numbering:
Letn. 7, št. 2
PID:
20.500.12556/DKUM-88240
UDC:
615.015.2
ISSN on article:
1855-5640
COBISS.SI-ID:
512465976
Publication date in DKUM:
11.04.2024
Views:
447
Downloads:
27
Metadata:
Categories:
Misc.
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Record is a part of a journal
Title:
Acta medico-biotechnica : AMB
Publisher:
Medicinska fakulteta, Medicinska fakulteta, Univerzitetna založba Univerze v Mariboru
ISSN:
1855-5640
COBISS.SI-ID:
242526720
Secondary language
Language:
Slovenian
Title:
Možne interakcije med kanabinoidi in estrogeni pri pogostih boleznih
Abstract:
Pred kratkim so odkrili prve molekularne povezave med kanabinoidnim sistemom in estrogeni. Preučevanje medsebojnega učinkovanja je zanimivo predvsem zato, ker bi lahko privedlo do novih farmakoterapevtskih pristopov, zlasti pri boleznih, kjer sta oba molekularna sistema vpletena v patofiziologijo bolezni. Članek predstavlja pregled vloge kanabinoidnega sistema in estrogenov pri osteoporozi, aterosklerozi in raku ter potencialne koristi medsebojne povezave obeh sistemov pri farmakoterapiji teh bolezni. Po obsežnem pregledu literature utemeljeno sklepamo na verjetno součinkovanje med kanabinoidnim sistemom in estrogeni, vendar ustreznih neposrednih študij na molekularnem nivoju v literaturi nismo zasledili. Z rezultati nedavne lastne raziskave na primarnih kulturah človeških osteoblastov smo prvi pokazali na morebitno molekularno součinkovanje med navedenima sistemoma. Potrebne so nadaljnje raziskave, ki bodo natančno preučile molekularno součinkovanje ter koristnosti in varnost posameznih kombinacij estrogenov in kanabinoidov v patogenezi oz. farmakoterapiji osteoporoze, ateroskleroze, rakavih in drugih pogostih obolenj.
Keywords:
estrogens
,
cannabinoids
,
osteoporosis
,
atherosclerosis
,
cancer
Collection
This document is a part of these collections:
Acta medico-biotechnica
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