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Title:Učinkovitost zdravljenja sindroma policističnih jajčnikov z metforminom
Authors:ID Jerenec, Katja (Author)
ID Samojlenko, Maša (Author)
ID Geršak, Ksenija (Author)
ID Ferk, Polonca (Author)
Files:URL http://www.actamedbio.mf.uni-mb.si/01_11id_amb_87_12.pdf
 
.pdf 01.pdf (400,88 KB)
MD5: 10B9B61AA4F13D80AE7E1B1C3C4DBD7E
 
Language:English
Work type:Scientific work
Typology:1.02 - Review Article
Organization:MF - Faculty of Medicine
Abstract:Metformin is an oral antidiabetic drug with potentially beneficial effects in patients with polycystic ovary syndrome (PCOS). Different pharmacological responses to metformin have been reported in PCOS patients, which may be attribut able to various clinical, biochemical, genetic and other factors. Here, we have outlined a short review of the results from current clinical studies on metformin efficacy in PCOS patients. Additionally, preliminary results from a retrospective pharmacogenetic study by our group on a sample of Slovene PCOS patients are presented. Pharmacogenetics is an emerging science that should provide options for individualized medicine, the future of healthcare.
Keywords:sindrom policističnih jajčnikov, metformin, farmakogenetika, osebna medicina
Publication status:Published
Publication version:Version of Record
Publication date:01.01.2013
Year of publishing:2013
Number of pages:str. 13-20
Numbering:Letn. 6, št. 2
PID:20.500.12556/DKUM-88252 New window
UDC:618.11-085
ISSN on article:1855-5640
COBISS.SI-ID:1165228 New window
Publication date in DKUM:12.04.2024
Views:337
Downloads:19
Metadata:XML DC-XML DC-RDF
Categories:Misc.
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Record is a part of a journal

Title:Acta medico-biotechnica : AMB
Publisher:Medicinska fakulteta, Medicinska fakulteta, Univerzitetna založba Univerze v Mariboru
ISSN:1855-5640
COBISS.SI-ID:242526720 New window

Secondary language

Language:Slovenian
Title:Efficacy of metformin treatment in polycysticovary syndrome : preučevanje celic beta v Langerhansovih otočkih
Abstract:Metformin je peroralni antidiabetik, potencialno učinkovit tudi v terapiji bolnic s sindromom policističnih jajčnikov (PCOS). Med bolnicami s PCOS prihaja do opaznih razlik v farmakološkem odzivu na metformin, kar je verjetno posledica kliničnih, biokemijskih, genetskih in drugih dejavnikov. V prispevku navajamo kratek pregled ugotovitev dosedanjih kliničnih študij učinkovitosti zdravljenja bolnic s PCOS z metforminom ter hkrati povzemamo preliminarne rezultate retrospektivne farmakogenetske študije na vzorcu slovenskih bolnic s PCOS. Sodobno znanje farmakogenetike si počasi, a vztrajno utira pot v klinično prakso ter postaja pomemben segment obravnave bolnikov in eden od temeljev osebne medicine medicine prihodnosti.
Keywords:polycystic ovary syndrome, metformin, pharmacogenetics, personalized medicine


Collection

This document is a part of these collections:
  1. Acta medico-biotechnica

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