| Title: | Human threat circuits : threats of pain, aggressive conspecific, and predator elicit distinct BOLD activations in the amygdala and hypothalamus |
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| Authors: | ID Bertram, Teresa (Author)
ID Hoffmann Ayala, Daniel (Author)
ID Huber, Eva Maria (Author)
ID Brandl, Felix (Author)
ID Starke, Georg (Author)
ID Sorg, Christian (Author)
ID Mulej Bratec, Satja (Author) |
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| Files: |  Bertram-2023-Human_threat_circuits__Threats_of.pdf (4,87 MB)
MD5: 90AEC9268B3EA7EA26A0815066EC09BC
 https://doi.org/10.3389/fpsyt.2022.1063238
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| Language: | English |
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| Work type: | Article |
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| Typology: | 1.01 - Original Scientific Article |
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| Organization: | FF - Faculty of Arts
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| Abstract: | Threat processing, enabled by threat circuits, is supported by a remarkably conserved neural architecture across mammals. Threatening stimuli relevant for most species include the threat of being attacked by a predator or an aggressive conspecific and the threat of pain. Extensive studies in rodents have associated the threats of pain, predator attack and aggressive conspecific attack with distinct neural circuits in subregions of the amygdala, the hypothalamus and the periaqueductal gray. Bearing in mind the considerable conservation of both the anatomy of these regions and defensive behaviors across mammalian species, we hypothesized that distinct brain activity corresponding to the threats of pain, predator attack and aggressive conspecific attack would also exist in human subcortical brain regions. |
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| Keywords: | human, threat responses, translational neuroscience, threat conditioning, threat types, MRI, threat circuit |
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| Publication status: | Published |
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| Publication version: | Version of Record |
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| Submitted for review: | 06.10.2022 |
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| Article acceptance date: | 16.12.2022 |
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| Publication date: | 09.01.2023 |
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| Publisher: | Frontiers Research Foundation |
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| Year of publishing: | 2023 |
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| Number of pages: | Str. 1-19 |
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| Numbering: | Letn. 13 |
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| PID: | 20.500.12556/DKUM-88276  |
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| UDC: | 159.96:616.89 |
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| ISSN on article: | 1664-0640 |
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| COBISS.SI-ID: | 137849347 |
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| DOI: | 10.3389/fpsyt.2022.1063238 |
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| Publication date in DKUM: | 12.04.2024 |
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| Views: | 547 |
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| Downloads: | 312 |
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| Metadata: |    |
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| Categories: | Misc.
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