| Title: | Dynamics of capillary lactate levels in patients with out-of-hospital cardiac arrest |
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| Authors: | ID Vujanović, Vitka (Author)
ID Borovnik Lesjak, Vesna (Author)
ID Mekiš, Dušan (Author)
ID Strnad, Matej (Author) |
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| Files: |  Vujanovic-2023-Dynamics_of_Capillary_Lactate_L.pdf (1,17 MB)
MD5: C180DEA7E0957A602DE17A05F1020241
 https://doi.org/10.3390/medicina59111989
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| Language: | English |
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| Work type: | Scientific work |
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| Typology: | 1.01 - Original Scientific Article |
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| Organization: | MF - Faculty of Medicine
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| Abstract: | Background and Objectives:
An effective strategy for cardiopulmonary resuscitation should be based on tissue perfusion. Our primary aim was to determine the association between capillary lactate values and initial rhythm as well as the probability of the return of spontaneous circulation in out-of-hospital cardiac arrest patients. Materials and
Methods:
This prospective observational cohort study included all patients with non-traumatic out-of-hospital cardiac arrest, older than 18 years, resuscitated by a prehospital emergency medical team between April 2020 and June 2021. Capillary lactate samples were collected at the time of arrival and every 10 min after the first measurement until the time of the return of spontaneous circulation (ROSC) or, if ROSC was not achieved, at the time of declaring death on the scene.
Results:
In total, 83 patients were enrolled in the study. ROSC was achieved in 28 patients (33.7%), 21 were admitted to hospital (26.3%), and 6 (7.23%) of them were discharged from hospital. At discharge, all patients had Cerebral Performance Category Scale 1 or 2. Initial capillary lactate values were significantly higher in patients with a non-shockable rhythm compared to the group with a shockable rhythm (9.19 ± 4.6 versus 6.43 ± 3.81; p = 0.037). A significant difference also persisted in a second value taken 10 min after the initial value (10.03 ± 5,19 versus 5.18 ± 3.47; p = 0.019). Capillary lactate values were higher in the ROSC group and non-ROSC group at the time of restored circulation (11.10 ± 6.59 and 6.77 ± 4.23, respectively; p = 0.047).
Conclusions:
Capillary lactate values are significantly higher in patients with a non-shockable first rhythm in out-of-hospital cardiac arrest (OHCA). There is also a significantly different rise in capillary lactate levels in patients with ROSC. |
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| Keywords: | cardiopulmonary resuscitation, out-of-hospital cardiac arrest, lactate, return of spontaneous circulation |
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| Publication status: | Published |
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| Publication version: | Version of Record |
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| Submitted for review: | 01.09.2023 |
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| Article acceptance date: | 06.11.2023 |
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| Publication date: | 11.11.2023 |
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| Publisher: | MDPI |
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| Year of publishing: | 2023 |
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| Number of pages: | Str. 1-11 |
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| Numbering: | Letn. 59, Št. 11, št. članka 1989 |
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| PID: | 20.500.12556/DKUM-88327  |
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| UDC: | 616.12-008.315 |
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| ISSN on article: | 1648-9144 |
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| COBISS.SI-ID: | 171801859 |
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| DOI: | 10.3390/medicina59111989 |
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| Publication date in DKUM: | 16.04.2024 |
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| Views: | 326 |
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| Downloads: | 38 |
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| Metadata: |    |
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| Categories: | Misc.
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