| Naslov: | Lipoprotein(a) as a risk factor in a cohort of hospitalised cardiovascular patients : A retrospective clinical routine data analysis |
|---|
| Avtorji: | ID Šuran, David (Avtor)
ID Završnik, Tadej (Avtor)
ID Kokol, Peter (Avtor)
ID Kokol, Marko (Avtor)
ID Sinkovič, Andreja (Avtor)
ID Naji, Franjo (Avtor)
ID Završnik, Jernej (Avtor)
ID Blažun Vošner, Helena (Avtor)
ID Kanič, Vojko (Avtor) |
|---|
| Datoteke: |  jcm-12-03220-v2.pdf (285,58 KB)
MD5: 9F6C7E699DCEEE836FCAAA0546EC8D1B
 https://www.mdpi.com/2077-0383/12/9/3220
|
|---|
| Jezik: | Angleški jezik |
|---|
| Vrsta gradiva: | Članek v reviji |
|---|
| Tipologija: | 1.01 - Izvirni znanstveni članek |
|---|
| Organizacija: | FERI - Fakulteta za elektrotehniko, računalništvo in informatiko
|
|---|
| Opis: | Lipoprotein(a) (Lp(a)) is a well-recognised risk factor for ischemic heart disease (IHD) and calcific aortic valve stenosis (AVS). Methods: A retrospective observational study of Lp(a) levels (mg/dL) in patients hospitalised for cardiovascular diseases (CVD) in our clinical routine was performed. The Lp(a)-associated risk of hospitalisation for IHD, AVS, and concomitant IHD/AVS versus other non-ischemic CVDs (oCVD group) was assessed by means of logistic regression. Results: In total of 11,767 adult patients, the association with Lp(a) was strongest in the IHD/AVS group (eβ = 1.010, p < 0.001), followed by the IHD (eβ = 1.008, p < 0.001) and AVS group (eβ = 1.004, p < 0.001). With increasing Lp(a) levels, the risk of IHD hospitalisation was higher compared with oCVD in women across all ages and in men aged ≤75 years. The risk of AVS hospitalisation was higher only in women aged ≤75 years (eβ = 1.010 in age < 60 years, eβ = 1.005 in age 60–75 years, p < 0.05). Conclusions: The Lp(a)-associated risk was highest for concomitant IHD/AVS hospitalisations. The differential impact of sex and age was most pronounced in the AVS group with an increased risk only in women aged ≤75 years. |
|---|
| Ključne besede: | acute myocardial infarction, aortic valve stenosis, atherosclerosis, cardiovascular diseases, cardiovascular risk, ischemic heart disease, lipoprotein(a), postmenopausal women |
|---|
| Status publikacije: | Objavljeno |
|---|
| Verzija publikacije: | Objavljena publikacija |
|---|
| Poslano v recenzijo: | 02.03.2023 |
|---|
| Datum sprejetja članka: | 27.04.2023 |
|---|
| Datum objave: | 29.04.2023 |
|---|
| Založnik: | MDPI |
|---|
| Leto izida: | 2023 |
|---|
| Št. strani: | [1]-10 str. |
|---|
| Številčenje: | Vol. 12, issue 9, [article no.] 3220 |
|---|
| PID: | 20.500.12556/DKUM-89079  |
|---|
| UDK: | 616.1 |
|---|
| COBISS.SI-ID: | 151715843 |
|---|
| DOI: | 10.3390/jcm12093220 |
|---|
| ISSN pri članku: | 2077-0383 |
|---|
| Avtorske pravice: | © 2023 by the authors |
|---|
| Datum objave v DKUM: | 12.06.2024 |
|---|
| Število ogledov: | 313 |
|---|
| Število prenosov: | 28 |
|---|
| Metapodatki: |    |
|---|
| Področja: | Ostalo
|
|---|
|
:
|
Kopiraj citat |
|---|
| | | | Skupna ocena: | (0 glasov) |
|---|
| Vaša ocena: | Ocenjevanje je dovoljeno samo prijavljenim uporabnikom. |
|---|
| Objavi na: |  |
|---|
Postavite miškin kazalec na naslov za izpis povzetka. Klik na naslov izpiše
podrobnosti ali sproži prenos. |
