| Title: | Kratek pregled platform za ADME testiranje |
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| Authors: | ID Maver, Tina (Author)
ID Vihar, Boštjan (Author)
ID Maver, Uroš (Author) |
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| Files: |  RAZ_Maver_Tina_2024.pdf (405,16 KB)
MD5: 64424AF733C77EA8B42E0054E6943B52
 http://dx.doi.org/10.18690/actabiomed.275
https://journals.um.si/index.php/amb/article/view/4757
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| Language: | English |
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| Work type: | Scientific work |
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| Typology: | 1.01 - Original Scientific Article |
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| Organization: | MF - Faculty of Medicine
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| Abstract: | V zadnjem času je bil dosežen pomemben napredek pri razvoju ADME (absorpcija, distribucija, metabolizem, ekskrecija) modelov, vendar izziv ostaja vzpostaviti platforme, ki bi zmanjšale testiranje na živalih in stroške raziskav. Naraščajoča pomembnost farmakokinetičnih interakcij poudarja potrebo po zanesljivih in
ponovljivih ADME modelih, ki so vse bolj ključni za razvoj zdravil in zagotavljanje varnosti z željo po preprečevanju
resnih kliničnih zapletov in hospitalizacije. |
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| Keywords: | ADME, drug interaction studies, in vitro models, pharmacokinetics, multi-organ models |
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| Publication status: | Published |
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| Publication version: | Version of Record |
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| Article acceptance date: | 08.11.2024 |
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| Publication date: | 19.11.2024 |
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| Publisher: | MF UM |
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| Year of publishing: | 2024 |
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| Number of pages: | str. 9-17 |
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| Numbering: | Letn. 17, št. 2 |
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| PID: | 20.500.12556/DKUM-91481  |
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| UDC: | 615 |
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| ISSN on article: | 1855-7988 |
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| COBISS.SI-ID: | 220447747 |
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| DOI: | 10.18690/actabiomed.275 |
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| Publication date in DKUM: | 07.01.2025 |
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| Views: | 184 |
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| Downloads: | 44 |
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| Metadata: |    |
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| Categories: | Misc.
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