| Naslov: | Optimization of the supercritical extraction and decarboxylation process of industrial hemp |
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| Avtorji: | ID Žitek Makoter, Taja (Avtor)
ID Kotnik, Petra (Avtor)
ID Makoter, Teo (Avtor)
ID Knez, Željko (Avtor)
ID Knez Marevci, Maša (Avtor) |
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| Datoteke: |  1-s2.0-S2212982024003421-main.pdf (10,15 MB)
MD5: 78A177C8CB3AB4CBECE13A60B41EBCC5
 https://www.sciencedirect.com/science/article/pii/S2212982024003421?via%3Dihub
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| Jezik: | Angleški jezik |
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| Vrsta gradiva: | Članek v reviji |
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| Tipologija: | 1.01 - Izvirni znanstveni članek |
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| Organizacija: | FKKT - Fakulteta za kemijo in kemijsko tehnologijo
MF - Medicinska fakulteta
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| Opis: | Cannabinoids are the main active ingredients of Cannabis sativa L., obtained by a suitable extraction method and decarboxylation, in which the acid forms of the cannabinoids are converted into active forms. Supercritical CO2 extraction method and decarboxylation process were optimized for 7 cannabinoids (CBD, CBDA, THC, THCA, CBGA, CBN and CBC). The optimal extraction conditions for all cannabinoids were determined at a temperature of 60 °C and a pressure of 300 bar to 550 bar. At higher temperatures and reaction times, a significant depletion of neutral cannabinoids was observed. The optimal conditions of the decarboxylation process varied depending on the component. For the CBD component, which could be measured in the highest concentrations (560 mg/g), the optimal conditions were 140 °C and 10 min. The study can be an important model for predicting the behavior of cannabinoids under certain parameters. |
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| Ključne besede: | supercritical fluids, extraction, cannabinoids, decarboxilation, Cannabis sativa I |
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| Status publikacije: | Objavljeno |
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| Verzija publikacije: | Objavljena publikacija |
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| Poslano v recenzijo: | 28.06.2024 |
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| Datum sprejetja članka: | 16.12.2024 |
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| Datum objave: | 21.12.2024 |
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| Založnik: | Elsevier |
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| Leto izida: | 2025 |
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| Št. strani: | 13 str. |
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| Številčenje: | Vol. 91, [article no.] 103007 |
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| PID: | 20.500.12556/DKUM-91501  |
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| UDK: | 66.02 |
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| COBISS.SI-ID: | 221113603 |
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| DOI: | 10.1016/j.jcou.2024.103007 |
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| ISSN pri članku: | 2212-9839 |
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| Avtorske pravice: | © 2024 The Author(s)
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| Datum objave v DKUM: | 08.01.2025 |
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| Število ogledov: | 206 |
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| Število prenosov: | 29 |
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| Metapodatki: |    |
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| Področja: | Ostalo
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