| Title: | Bromelain and nisin: The natural antimicrobials with high potential in biomedicine |
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| Authors: | ID Jančič, Urška (Author)
ID Gorgieva, Selestina (Author) |
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| Files: |  pharmaceutics-14-00076.pdf (13,18 MB)
MD5: 574954CA2D5E9422B1E020C2715DE0B9
 https://www.mdpi.com/1999-4923/14/1/76
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| Language: | English |
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| Work type: | Article |
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| Typology: | 1.02 - Review Article |
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| Organization: | FS - Faculty of Mechanical Engineering
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| Abstract: | Infectious diseases along with various cancer types are among the most significant public
health problems and the leading cause of death worldwide. The situation has become even more
complex with the rapid development of multidrug-resistant microorganisms. New drugs are urgently
needed to curb the increasing spread of diseases in humans and livestock. Promising candidates
are natural antimicrobial peptides produced by bacteria, and therapeutic enzymes, extracted from
medicinal plants. This review highlights the structure and properties of plant origin bromelain and
antimicrobial peptide nisin, along with their mechanism of action, the immobilization strategies, and
recent applications in the field of biomedicine. Future perspectives towards the commercialization of
new biomedical products, including these important bioactive compounds, have been highlighted. |
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| Keywords: | bromelain, nisin, bioactivity, antimicrobial agent, biomedicine, carrier |
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| Publication status: | Published |
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| Publication version: | Version of Record |
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| Submitted for review: | 22.11.2021 |
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| Article acceptance date: | 23.12.2021 |
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| Publication date: | 29.12.2021 |
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| Publisher: | MDPI AG |
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| Year of publishing: | 2022 |
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| Number of pages: | str. 1-39 |
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| Numbering: | Vol. 14, iss. 1 |
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| PID: | 20.500.12556/DKUM-92279  |
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| UDC: | 577:543.2/.9 |
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| ISSN on article: | 1999-4923 |
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| COBISS.SI-ID: | 91691779 |
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| DOI: | 10.3390/pharmaceutics14010076 |
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| Copyright: | © 2021 by the authors |
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| Publication date in DKUM: | 27.03.2025 |
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| Views: | 157 |
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| Downloads: | 8 |
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| Metadata: |    |
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| Categories: | Misc.
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