| Title: | Artificial biomimetic electrochemical assemblies |
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| Authors: | ID Zidarič, Tanja (Author)
ID Finšgar, Matjaž (Author)
ID Maver, Uroš (Author)
ID Maver, Tina (Author) |
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| Files: |  biosensors-12-00044-v2.pdf (5,11 MB)
MD5: 53C7A9035EA45D0EF2D92E0F8EDE1151
 https://www.mdpi.com/2079-6374/12/1/44
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| Language: | English |
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| Work type: | Article |
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| Typology: | 1.02 - Review Article |
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| Organization: | FKKT - Faculty of Chemistry and Chemical Engineering
MF - Faculty of Medicine
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| Abstract: | Rapid, selective, and cost-effective detection and determination of clinically relevant
biomolecule analytes for a better understanding of biological and physiological functions are becoming increasingly prominent. In this regard, biosensors represent a powerful tool to meet these
requirements. Recent decades have seen biosensors gaining popularity due to their ability to design
sensor platforms that are selective to determine target analytes. Naturally generated receptor units
have a high affinity for their targets, which provides the selectivity of a device. However, such
receptors are subject to instability under harsh environmental conditions and have consequently low
durability. By applying principles of supramolecular chemistry, molecularly imprinted polymers
(MIPs) can successfully replace natural receptors to circumvent these shortcomings. This review summarizes the recent achievements and analytical applications of electrosynthesized MIPs, in particular,
for the detection of protein-based biomarkers. The scope of this review also includes the background
behind electrochemical readouts and the origin of the gate effect in MIP-based biosensors. |
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| Keywords: | MIP-based biosensors, MIP, biosensors, molecularly imprinted polymer, biomolecules, electroanalysis |
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| Publication status: | Published |
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| Publication version: | Version of Record |
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| Submitted for review: | 10.12.2021 |
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| Article acceptance date: | 04.01.2022 |
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| Publication date: | 15.01.2022 |
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| Publisher: | MDPI AG |
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| Year of publishing: | 2022 |
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| Number of pages: | 38 str. |
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| Numbering: | Vol. 12, iss. 1 |
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| PID: | 20.500.12556/DKUM-92822  |
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| UDC: | 543.2/.9 |
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| ISSN on article: | 2079-6374 |
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| COBISS.SI-ID: | 93877763 |
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| DOI: | 10.3390/bios12010044 |
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| Copyright: | © 2022 by the authors |
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| Publication date in DKUM: | 15.05.2025 |
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| Views: | 205 |
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| Downloads: | 11 |
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| Metadata: |    |
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| Categories: | Misc.
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