Študija prenosa toplote iz police liofilizatorja na viale

Šantl, Jakob

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Title:	Študija prenosa toplote iz police liofilizatorja na viale
Authors:	ID Šantl, Jakob (Author) ID Hriberšek, Matjaž (Mentor) More about this mentor... ID Kamenik, Blaž (Comentor)
Files:	UN_Santl_Jakob_2025.pdf (4,39 MB) MD5: E11D459E75797F439F7E13F858CAB039
Language:	Slovenian
Work type:	Bachelor thesis/paper
Typology:	2.11 - Undergraduate Thesis
Organization:	FS - Faculty of Mechanical Engineering
Abstract:	V diplomskem delu je predstavljena študija prenosa toplote iz police liofilizatorja na viale. Predstavljeno je teoretsko ozadje prenosa toplote ter procesa liofilizacije. S pomočjo numeričnih simulacij smo analizirali prenos toplote na realno ter poenostavljeno geometrijo viale 10R, pri čemer smo z definiranjem toplotnega upora med vialo in polico liofilizatorja poenostavljene geometrije opisali toplotne razmere v realni viali. Rezultate simulacij smo primerjali z eksperimentalno pridobljenimi temperaturnimi poteki ohlajanja destilirane vode v vialah. V diplomskem delu smo ugotovili, da je za validacijo numerične simulacije z eksperimentalnimi rezultati ključno poznavanje masnega toka grelno-hladilnega medija v policah liofilizatorja, ki bistveno vpliva na intenziteto prenosa toplote iz polic liofilizatorja na viale.
Keywords:	prenos toplote, liofilizacija, računalniška dinamika tekočin, viala
Place of publishing:	Maribor
Publisher:	[J. Šantl]
Year of publishing:	2025
PID:	20.500.12556/DKUM-95102
UDC:	536.24(043.2)
COBISS.SI-ID:	21958
Publication date in DKUM:	02.10.2025
Views:	149
Downloads:	50
Metadata:
Categories:	KTFMB - FS
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Licences

License:	CC BY-NC-ND 4.0, Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International

Link:	http://creativecommons.org/licenses/by-nc-nd/4.0/
Description:	The most restrictive Creative Commons license. This only allows people to download and share the work for no commercial gain and for no other purposes.
Licensing start date:	04.09.2025

Secondary language

Language:	English
Title:	Study of the heat transfer from the lyophilizer shelf to the vials
Abstract:	This thesis presents a study of heat transfer from the shelf of a lyophilizer to the vials. The theoretical background of heat transfer and the lyophilization process is first introduced. Using numerical simulations, we analyzed heat transfer on both the real and simplified geometry of a 10R vial. By defining the thermal resistance between the vial and the shelf of the lyophilizer, the simplified geometry was used to represent the thermal conditions in a real vial. The simulation results were compared with experimentally obtained temperature profiles of distilled water cooling inside the vials. The findings of this thesis show that accurate knowledge of the mass flow rate of the heating–cooling medium in the lyophilizer shelves is crucial for validating the numerical simulations against experimental results, as it significantly influences the intensity of heat transfer from the shelves to the vials.
Keywords:	heat transfer, lyophilization, computational fluid dynamics, vial

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