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Title:Memantine Associated With Parkinsonism in a Patient With Alzheimer’s Disease : A Case Study and the Review of the Literature
Authors:ID Štuhec, Matej (Author)
Files:.pdf Memantine_Associated-Stuhec-.pdf (659,18 KB)
MD5: CEF1F5D066AC70E116E2A0F74A586BE1
 
URL https://journals.um.si/index.php/anali-pazu/sl/article/view/1970
 
Language:English
Work type:Scientific work
Typology:1.02 - Review Article
Organization:UZUM - University of Maribor Press
Abstract:The positive effect of memantine on parkinsonism has been reported widely, but there have not been reports in the literature of parkinsonism, tremor and bradykinesis, induced by memantine, in an Alzheimer's patient, who did not have Parkinson's disease or a history of antipsychotic agents. In this case study, we report parkinsonism, tremor and night bradykinesis induced by memantine use (5 mg daily) in a 83-year-old Slovenian female patient. After memantine discontinuation, suggested by a clinical pharmacist specialist, and switching to donepezil 5 mg, the adverse drug reactions disappeared the next day. This case study may serve to help clinicians and clinical pharmacists distinguish memantine-induced parkinsonism from more serious conditions.
Keywords:parkinsonism, adverse event, literature review, Alzheimer's disease, clinical pharmacy
Publication status:Published
Publication version:Version of Record
Publication date:01.01.2016
Place of publishing:Maribor
Publisher:Univerza v Mariboru, Univerzitetna založba
Year of publishing:2016
Number of pages:4
Numbering:Letn.5, št.1/2
PID:20.500.12556/DKUM-97356 New window
UDC:616.858
ISSN on article:2820-364X
COBISS.SI-ID:14008883 New window
DOI:10.18690/analipazu.5.1-2.6-9.2015 New window
Publication date in DKUM:02.03.2026
Views:260
Downloads:3
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Categories:Misc.
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Record is a part of a journal

Title:Anali PAZU
Publisher:Združenje Pomurska akademsko znanstvena unija, Združenje Pomurska akademsko znanstvena unija, Univerzitetna založba Univerze v Mariboru
ISSN:2232-416X
COBISS.SI-ID:257553152 New window

Licences

License:CC BY-NC-ND 4.0, Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
Link:http://creativecommons.org/licenses/by-nc-nd/4.0/
Description:The most restrictive Creative Commons license. This only allows people to download and share the work for no commercial gain and for no other purposes.

Secondary language

Language:Slovenian
Title:Parkinsonizem povzročen z memantinom pri bolniku z Alzheimerjevo boleznijo : študija primera in pregled literature
Abstract:Pozitivni učinki memantina na parkinsonizem so pogosto opisani, a parkinsonizem, tremor, bradikinezija povzročeni z memantinom, brez zgodovine zdravljenja z antipsihotiki, pri bolniku z Alzheimerjevo boleznijo v literaturi še niso bili opisani. V tej študiji primera prikazujemo z memantinom (5 mg dnevno) povzročen parkinsonizem, tremor in bradikinezijo pri 83-letni slovenski bolnici. Po ukinitvi zdravljenja z memantinom in uvedbo donepezila 5 mg dnevno, svetovano s strani kliničnega farmacevta specialista, so se neželeni učinki umaknili naslednji dan. Ta študija primera lahko služi kot pomoč zdravnikom in kliničnim farmacevtom v razlikovanju z memantinom povzročenega parkinsonizma od bolj resnih stanj.
Keywords:parkinsonizem, neželeni dogodek, pregled literature, Alzheimerjeva bolezen, klinična farmacija


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  1. Anali PAZU

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