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Title:Development and evaluation of a generative AI chatbot for database searching in systematic review
Authors:ID Tam, Wilson (Author)
ID Tung, Neo (Author)
ID Lee, Shi Xuan (Author)
ID Štiglic, Gregor (Author)
ID Huynh, Tom (Author)
ID Tang, Arthur (Author)
Files:.pdf J_of_Nursing_Scholarship_-_2026_-_Tam_-_Development_and_Evaluation_of_a_Generative_AI_Chatbot_for_Database_Searching_in.pdf (1,09 MB)
MD5: 8498E1E2F58433264ACFA44F9AE8B076
 
URL https://sigmapubs.onlinelibrary.wiley.com/doi/10.1111/jnu.70076
 
Language:English
Work type:Scientific work
Typology:1.01 - Original Scientific Article
Organization:FZV - Faculty of Health Sciences
Abstract:Introduction Systematic reviews (SRs) require comprehensive, reproducible searches, yet developing search strategies is resource-intensive and demands specialized expertise. Generative AI offers potential to streamline this process, but empirical evaluations for GAI-assisted SR searching remain scarce. The objectives of this study are to: demonstrate a step-by-step process for developing a custom ChatGPT-based chatbot to support SR search strategy development, and evaluate its performance. Design A cross-sectional evaluation study. Methods We used ChatGPT-4.0 to create a chatbot designed to mimic a medical librarian, generating PICO-informed searches. Its knowledge base was augmented with two methodological references. After piloting testing, we refined its instructions. For evaluation, we randomly sampled 50 Cochrane SRs published in 2024. Standardized P–I–O prompts produced database-ready queries for PUBMED and EMBASE. The primary outcome was per-review success rate, summarized by median and inter-quartile range. A sensitivity analysis was conducted. Results Pilot testing achieved a retrieval rate of 41/49 (83.7%). In the main sample (1169 studies; median 13.5 studies per SR), the chatbot identified a median of 67.4% of included studies (IQR: 43.1%–88.4%). When limited to indexed studies (n = 1114), retrieval rose to 72.0% (IQR: 46.0%–92.5%). Lower performance was observed when outcomes were absent from the abstracts or interventions had many lexical variants. Conclusions A GAI-based chatbot can rapidly generate SR searches (~67%–72% identification), serving as a useful starting point but not a replacement for expert-led approaches. Integration of librarian expertise, structured prompts, and controlled vocabularies may improve performance. Further benchmarking and transparent reporting are needed to guide adoption.
Keywords:database searching, generative artificial intelligence, large language model, systematic review
Publication status:Published
Publication version:Version of Record
Submitted for review:13.10.2025
Article acceptance date:17.02.2026
Publication date:10.03.2026
Publisher:Wiley
Year of publishing:2026
Number of pages:str. 1-7
Numbering:Letn. 58, št. 2, št. članka e70076
PID:20.500.12556/DKUM-97514 New window
UDC:007.52+004.8:025.4.036:004.65
ISSN on article:1547-5069
COBISS.SI-ID:271552515 New window
DOI:10.1111/jnu.70076 New window
Publication date in DKUM:19.03.2026
Views:225
Downloads:2
Metadata:XML DC-XML DC-RDF
Categories:Misc.
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Licences

License:CC BY-NC-ND 4.0, Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
Link:http://creativecommons.org/licenses/by-nc-nd/4.0/
Description:The most restrictive Creative Commons license. This only allows people to download and share the work for no commercial gain and for no other purposes.
Licensing start date:10.03.2026

Secondary language

Language:Slovenian
Keywords:razvoj iskalnih strategij, generativna umetna inteligenca, veliki jezikovni model, sistematični pregledi


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