| Title: | Flavourings, nicotine content, and elemental composition as indicators of regulatory compliance in nicotine pouches and heated tobacco products |
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| Authors: | ID Rantaša, Matjaž (Author)
ID Finšgar, Matjaž (Author) |
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| Files: |  d6an00153j_(1).pdf (2,06 MB)
MD5: 72BF52E2246A20F93941465A3B1A9D2E
 https://pubs.rsc.org/an/article/151/10/2962/1233946/Flavourings-nicotine-content-and-elemental
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| Language: | English |
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| Work type: | Article |
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| Typology: | 1.01 - Original Scientific Article |
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| Organization: | FKKT - Faculty of Chemistry and Chemical Engineering
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| Abstract: | Nicotine pouches (NPs) and heated tobacco products using heatsticks (HSs) are relatively new alternatives to traditional smoking. Their rising popularity, especially among younger populations, and recent regulatory efforts to reduce nicotine and tobacco use, emphasize the need for their analytical assessment. In this study, the chemical composition of 26 NPs and 16 HSs available on the Slovenian market has been investigated. Non-targeted gas chromatography-mass spectrometry analysis showed that some HSs contained compounds not permitted under regulations, including menthol, vanillin, and ethyl vanillin. NPs, which are not yet regulated regarding flavouring additives, contained potentially harmful compounds (cinnamaldehyde, acetaldehyde, menthofurane, pulegone, D-limonene, etc.), many of which were not declared on the product labels. Tobacco-based HSs contained significantly higher total element content (up to 2155.32 µg g−1) compared to cellulose-based NPs (up to 61.21 µg g−1), with Al, Ba, Fe, Mn, Sr, and Ti being the most abundant. Nicotine content ranged from 7.6 ± 0.2 mg g−1 of NP filling to 20.0 ± 0.1 mg g−1 of NP filling in NPs and from 12.6 ± 0.1 mg g−1 of HS filling to 16.6 ± 0.1 mg g−1 of HS filling in HSs. The determined nicotine content in NPs deviated up to −52.9% from that declared by the manufacturers. These findings highlight the variability in the chemical composition of NPs and HSs, including their flavourings, nicotine content, and elemental composition, emphasizing the need for regulatory oversight and correct product labelling. |
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| Keywords: | nicotine, heated tobacco, falvourings |
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| Publication status: | Published |
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| Publication version: | Version of Record |
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| Submitted for review: | 06.02.2026 |
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| Article acceptance date: | 08.04.2026 |
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| Publication date: | 09.04.2026 |
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| Publisher: | Royal Society of Chemistry |
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| Year of publishing: | 2026 |
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| Number of pages: | 16 str. |
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| PID: | 20.500.12556/DKUM-97911  |
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| UDC: | 661 |
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| ISSN on article: | 1364-5528 |
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| COBISS.SI-ID: | 275525635 |
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| DOI: | 10.1039/d6an00153j |
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| Publication date in DKUM: | 24.04.2026 |
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| Views: | 522 |
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| Downloads: | 9 |
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| Metadata: |    |
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| Categories: | Misc.
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