| Title: | Inhibitory synaptic timescales drive oscillatory regime transitions in recurrent excitatory-inhibitory networks |
|---|
| Authors: | ID Kheiri, Siamak (Author)
ID Taghavi, Saeed (Author)
ID Perc, Matjaž (Author)
ID Valizadeh, Alireza (Author) |
|---|
| Files: |  RAZ_Kheiri_Siamak_2026.pdf (5,70 MB)
MD5: 492F87A9D834DC6BBF9AD1F4FBAADC5C
 https://doi.org/10.1103/zmn7-7kf6
|
|---|
| Language: | English |
|---|
| Work type: | Scientific work |
|---|
| Typology: | 1.01 - Original Scientific Article |
|---|
| Organization: | FNM - Faculty of Natural Sciences and Mathematics
|
|---|
| Abstract: | In recurrent cortical networks, inhibitory kinetics are often assumed to tune oscillation frequency continuously. Using a recurrent excitatory-inhibitory (E-I) model with fixed excitatory synaptic dynamics, we systematically vary inhibitory decay time constants and show instead that inhibitory timescale acts as a control parameter that drives sharp transitions between distinct collective states. The network switches between a coherent high-frequency regime and a coherent gamma-band regime, separated by an intermediate transition state with reduced synchrony and unstable phase coordination. Phase analysis demonstrates that the coherent regimes exhibit distinct, internally consistent E-I coordination patterns, whereas these relationships break down in the transition regime. Dissecting inhibitory pathways reveals that inhibitory-to-inhibitory decay times determine the operative regime, while inhibitory-to-excitatory kinetics primarily adjust oscillation frequency and the width of the transition region without altering the global phase structure. Our results link physiological diversity in inhibitory synaptic timescales to discrete oscillatory regimes in recurrent cortical circuits. |
|---|
| Keywords: | biological neural networks, inhibitory synapses, neuronal dynamics, spiking neurons, synchronization |
|---|
| Publication status: | Published |
|---|
| Publication version: | Version of Record |
|---|
| Article acceptance date: | 11.05.2026 |
|---|
| Publication date: | 05.06.2026 |
|---|
| Place of publishing: | College Park |
|---|
| Publisher: | American Phyisical Society |
|---|
| Year of publishing: | 2026 |
|---|
| Number of pages: | 12 str. |
|---|
| Numbering: | Letn. 8, št. 2, št. članka 023251 |
|---|
| PID: | 20.500.12556/DKUM-98390  |
|---|
| UDC: | 53:57.087.1 |
|---|
| ISSN on article: | 2643-1564 |
|---|
| COBISS.SI-ID: | 281016579 |
|---|
| DOI: | 10.1103/zmn7-7kf6 |
|---|
| Publication date in DKUM: | 09.06.2026 |
|---|
| Views: | 302 |
|---|
| Downloads: | 2 |
|---|
| Metadata: |    |
|---|
| Categories: | Misc.
|
|---|
|
:
|
Copy citation |
|---|
| | | | Average score: | (0 votes) |
|---|
| Your score: | Voting is allowed only for logged in users. |
|---|
| Share: |  |
|---|
Hover the mouse pointer over a document title to show the abstract or click
on the title to get all document metadata. |
