| Title: | A higher amount of nutritional intake as a possible cause of hyperglycemia in extremely premature infants in parenteral and enteral nutrition at the tertiary neonatal intensive care unit |
|---|
| Authors: | ID Predanič Drobne, Iza (Author)
ID Kornhauser-Cerar, Lilijana (Author)
ID Erčulj, Vanja (Author)
ID Grosek, Štefan (Corresponding author) |
|---|
| Files: |  A_Higher_Amount_of_Nutrit-Predanic_Drobne-2023.pdf (258,17 KB)
MD5: 0E7EA90E3EFEF2AE77E5CC0AE33EF6D2
 https://www.mdpi.com/2227-9067/10/10/1651
|
|---|
| Language: | English |
|---|
| Work type: | Scientific work |
|---|
| Typology: | 1.01 - Original Scientific Article |
|---|
| Organization: | FVV - Faculty of Criminal Justice and Security
|
|---|
| Abstract: | Background: This study aimed to find an association between infants who had hyperglycemia and those who did not, those treated with insulin or not and several prenatal and postnatal variables or the suboptimal prescription of parenteral nutrition. Methods: We conducted a retrospective study, which included extremely premature infants (<28 weeks of gestation) admitted to the tertiary NICU, University Medical Centre Ljubljana, between 1 January 2021 and 31 December 2021. Blood glucose measurements, insulin treatment, general characteristics, nutritional data and complications of prematurity were obtained retrospectively from hospital data. Results: There were 21 infants included in the study who did not receive insulin and 17 who were treated with insulin. Infants receiving insulin were younger and lighter compared to the non-insulin treatment group (mean gestational age 178 vs. 188 days; median birth weight 680 g vs. 990 g). The younger insulin group of infants received the same daily number of total macronutrients per kg per day compared to the older non-insulin group, i.e., glucose, lipids and amino acids, as recommended for the gestational age and birth weight. After adjusting for gestational age, no significant association with complications of prematurity was found. Conclusions: The postulated explanation (with the prescription of a higher amount of macronutrients during the first seven days) for hyperglycemia and treatment with insulin in the less mature and lighter infants cannot be supported by the data given. |
|---|
| Keywords: | hyperglycemia, extremely premature infants, nutritional intake, parenteral nutrition, complications of prematurity |
|---|
| Publication status: | Published |
|---|
| Publication version: | Version of Record |
|---|
| Submitted for review: | 23.08.2023 |
|---|
| Article acceptance date: | 02.10.2023 |
|---|
| Publication date: | 04.10.2023 |
|---|
| Year of publishing: | 2023 |
|---|
| Number of pages: | str. 1-9 |
|---|
| Numbering: | Letn. 10, št. 10, št. članka 1651 |
|---|
| PID: | 20.500.12556/DKUM-99229  |
|---|
| UDC: | 616-053.2:618.2/.7 |
|---|
| ISSN on article: | 2227-9067 |
|---|
| COBISS.SI-ID: | 171111939 |
|---|
| DOI: | 10.3390/children10101651 |
|---|
| NUK URN: | URN:SI:UM:DK:B2KUUOUO |
|---|
| Publication date in DKUM: | 17.08.2026 |
|---|
| Views: | 214 |
|---|
| Downloads: | 4 |
|---|
| Metadata: |    |
|---|
| Categories: | Misc.
|
|---|
|
:
|
Copy citation |
|---|
| | | | Average score: | (0 votes) |
|---|
| Your score: | Voting is allowed only for logged in users. |
|---|
| Share: |  |
|---|
Hover the mouse pointer over a document title to show the abstract or click
on the title to get all document metadata. |
