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Title:The role of quantitative hemodynamic magnetic resonance imaging in the surgical revascularization of cerebral tissue
Authors:ID Šebök, Martina (Author)
Files:.pdf RAZ_Sebok_Martina_2026.pdf (1,21 MB)
MD5: 6CBB09C58660E528D67817CCB1A35871
 
URL https://journals.um.si/index.php/anali-pazu/article/view/6281
 
Language:English
Work type:Scientific work
Typology:1.01 - Original Scientific Article
Organization:FNM - Faculty of Natural Sciences and Mathematics
UZUM - University of Maribor Press
Abstract:The goal of surgical revascularization of brain tissue is to improve cerebral perfusion in patients with cerebrovascular stenotic-occlusive disease, where certain regions of the brain are hypoperfused. The most commonly performed procedure, anastomosis between the superficial temporal artery and middle cerebral artery (STA-MCA bypass), is indicated in moyamoya vasculopathy, in selected cases of chronic stenotic-occlusive disease, and in acute ischemic stroke with hemodynamic impairment. Quantitative hemodynamic assessment plays a key role in selecting candidates for the procedure. Among modern non-invasive methods for assessing cerebral hemodynamics, blood oxygenation-level dependent cerebrovascular reactivity (BOLD-CVR) stands out. This special form of magnetic resonance imaging allows detection of regions with reduced vasodilatory capacity, thereby identifying hemodynamically endangered brain tissue. This article presents the current indications and decision-making processes in selecting patients for surgical revascularization of the brain, as well as institutional experiences in patient selection based on BOLD-CVR. The critical importance of this method for successful planning and execution of revascularization is emphasized, as it significantly contributes to optimizing surgical and clinical outcomes.
Keywords:surgical cerebral revascularization, STA-MCA bypass, cerebrovascular steno-occlusive disease, cerebral hemodynamics, functional magnetic resonance imaging
Publication status:Published
Publication version:Version of Record
Publication date:31.07.2026
Year of publishing:2026
Number of pages:str. 75-88
Numbering:Letn. 16, št. 1/2
PID:20.500.12556/DKUM-99472 New window
UDC:616.831-089
ISSN on article:2232-416X
COBISS.SI-ID:288028675 New window
DOI:10.18690/analipazu.16.1-2.75-88.2026 New window
Publication date in DKUM:18.08.2026
Views:160
Downloads:1
Metadata:XML DC-XML DC-RDF
Categories:Misc.
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Record is a part of a journal

Title:Anali PAZU
Publisher:Združenje Pomurska akademsko znanstvena unija, Združenje Pomurska akademsko znanstvena unija, Univerzitetna založba Univerze v Mariboru
ISSN:2232-416X
COBISS.SI-ID:257553152 New window

Licences

License:CC BY 4.0, Creative Commons Attribution 4.0 International
Link:http://creativecommons.org/licenses/by/4.0/
Description:This is the standard Creative Commons license that gives others maximum freedom to do what they want with the work as long as they credit the author.
Licensing start date:31.07.2026

Secondary language

Language:Slovenian
Title:Vloga kvantitativne hemodinamske magnetne resonance pri kirurški revaskularizaciji možganskega tkiva
Abstract:Cilj kirurške revaskularizacije možganskega tkiva je izboljšati možgansko perfuzijo pri bolnikih s cerebrovaskularno steno-okluzivno boleznijo, pri katerih so določene regije možganov slabo prekrvavljene. Najpogosteje izveden poseg, anastomoza med površinsko temporalno in srednjo možgansko arterijo (STA-MCA bypass), je indiciran pri moyamoya vaskulopatiji, pri izbranih primerih kronične steno-okluzivne bolezni in akutne ishemične možganske kapi s hemodinamsko prizadetostjo. Kvantitativna hemodinamska ocena ima ključno vlogo pri odločanju o kandidatih za poseg. Med sodobnimi neinvazivnimi metodami za oceno možganske hemodinamike izstopa BOLD-CVR (blood oxygenation-level dependent cerebrovascular reactivity), posebna oblika magnetnoresonančnega slikanja, ki omogoča zaznavo regij z zmanjšano vazodilatacijsko sposobnostjo in s tem identifikacijo hemodinamsko ogroženega možganskega tkiva. V tem članku so predstavljene aktualne indikacije in postopki odločanja pri izbiri bolnikov za kirurško revaskularizacijo možganov ter institucionalne izkušnje pri selekciji bolnikov na osnovi BOLD-CVR. Poudarjen je ključni pomen te metode za uspešno načrtovanje in izvedbo revaskularizacije, kar pomembno prispeva k optimizaciji kirurških in kliničnih izidov.
Keywords:kirurška revaskularizacija možganov, STA-MCA bypass, cerebrovaskularna steno-okluzivna bolezen, možganska hemodinamika, funkcijska magnetna resonanca


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