| Title: | Acute kidney injury after open-heart surgery procedures |
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| Authors: | ID Djordjević, Anže (Author)
ID Šušak, Stamenko (Author)
ID Velicki, Lazar (Author)
ID Antonič, Miha (Author) |
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| Files: |  Djordjevic-2021-ACUTE_KIDNEY_INJURY_AFTER_OPEN.pdf (247,36 KB)
MD5: 85DCE64E8D2D28712556E754A77AF77F
 https://doi.org/10.20471/acc.2021.60.01.17
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| Language: | English |
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| Work type: | Scientific work |
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| Typology: | 1.02 - Review Article |
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| Organization: | MF - Faculty of Medicine
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| Abstract: | Cardiac surgery-associated acute kidney injury (CS-AKI) is a major complication associated with increased morbidity and mortality. There are multiple diagnostic criteria for CS-AKI. Despite many new investigations available for improved AKI diagnostics, creatinine and urea remain the cornerstone of diagnostics in everyday clinical practice. There are three major pathophysiological mechanisms that contribute to kidney injury, i.e. renal hypoperfusion, inflammation with oxidative stress, and use of nephrotoxic agents. Some risk factors have been identified that can be modified during the course of treatment (use of nephrotoxic agents, duration of cardiopulmonary bypass, type of extracorporeal circulation, postoperative low cardiac output or hypotension). The aim of AKI prevention should always be to prevent aggravation of renal failure and, if possible, to avoid progression to renal replacement therapy, which in turn brings worse long-term outcomes. |
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| Keywords: | kidney injuries, cardiac surgery, perfusion, oxidative stress, dialysis |
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| Publication status: | Published |
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| Publication version: | Version of Record |
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| Publication date: | 01.03.2021 |
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| Publisher: | Sestre milosrdnice University Hospital, Institute for Clinical Medical Research |
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| Year of publishing: | 2021 |
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| Number of pages: | Str. 120-126 |
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| Numbering: | Letn. 60, Št. 1 |
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| PID: | 20.500.12556/DKUM-89754  |
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| UDC: | 616.12-089 |
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| ISSN on article: | 1333-9451 |
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| COBISS.SI-ID: | 70352387 |
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| DOI: | 10.20471/acc.2021.60.01.17 |
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| Note: | Ključne besede v slovenščini: poškodbe ledvic, srčna kirurgija, perfuzija, oksidativni stres, dializa |
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| Publication date in DKUM: | 09.08.2024 |
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| Views: | 539 |
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| Downloads: | 17 |
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| Metadata: |    |
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| Categories: | Misc.
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