| Title: | Development of fluorescence-based method for dopamine determination using o-phthaldialdehyde and 3-mercaptopropyltriethoxysilane |
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| Authors: | ID Sliesarenko, Valeriia V. (Author)
ID Krstić, Marijana (Author)
ID Bren, Urban (Author)
ID Lobnik, Aleksandra (Author) |
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| Files: |  sensors-25-01729.pdf (3,17 MB)
MD5: 8C114D613CCBA920A8A46F79C9DE924C
 https://www.mdpi.com/1424-8220/25/6/1729
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| Language: | English |
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| Work type: | Article |
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| Typology: | 1.01 - Original Scientific Article |
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| Organization: | FKKT - Faculty of Chemistry and Chemical Engineering
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| Abstract: | Nanomaterials and sensors play an important role in modern technologies, including medical diagnostics and biochemical research. This work presents the possibility of using o-Phthaldialdehyde (OPA) in combination with 3-mercaptopropyltriethoxysilane (MPTES) to develop a dopamine-responsive sensor. During the experiment, these materials were used at different pH and ratios to determine the optimal parameters for obtaining high fluorescence intensity of the reaction product. The data obtained demonstrate a linear relationship between the fluorescence response (λex/λem = 340/460 nm) of OPA/MPTES and dopamine concentration in the range of 0.1–3.0 µM at a pH of 8, and the detection limit was 8.7 nM. The obtained results confirm the potential of OPA/MPTES as a sensing component for the detection of dopamine |
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| Keywords: | fluorometric method, dopamine, o-phthalaldehyde |
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| Publication status: | Published |
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| Publication version: | Version of Record |
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| Submitted for review: | 30.01.2025 |
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| Article acceptance date: | 07.03.2025 |
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| Publication date: | 11.03.2025 |
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| Publisher: | MDPI |
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| Year of publishing: | 2025 |
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| Number of pages: | 14 str. |
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| Numbering: | Vol. 25, iss. 6, [article no.] 1729 |
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| PID: | 20.500.12556/DKUM-92051  |
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| UDC: | 66 |
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| ISSN on article: | 1424-8220 |
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| COBISS.SI-ID: | 228846339 |
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| DOI: | 10.3390/s25061729 |
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| Copyright: | © 2025 by the authors |
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| Publication date in DKUM: | 13.03.2025 |
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| Views: | 110 |
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| Downloads: | 11 |
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| Metadata: |    |
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| Categories: | Misc.
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