| Naslov: | Optimisation of the green process of industrial hemp - preparation and its extract characterisation |
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| Avtorji: | ID Žitek Makoter, Taja (Avtor)
ID Kotnik, Petra (Avtor)
ID Makoter, Teo (Avtor)
ID Postružnik, Vesna (Avtor)
ID Knez, Željko (Avtor)
ID Knez Marevci, Maša (Avtor) |
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| Datoteke: |  plants-11-01749-v3.pdf (1,96 MB)
MD5: 2A266CB55E560962A56A3E6E178770A2
 https://www.mdpi.com/2223-7747/11/13/1749
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| Jezik: | Angleški jezik |
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| Vrsta gradiva: | Članek v reviji |
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| Tipologija: | 1.01 - Izvirni znanstveni članek |
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| Organizacija: | FKKT - Fakulteta za kemijo in kemijsko tehnologijo
FS - Fakulteta za strojništvo
MF - Medicinska fakulteta
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| Opis: | Natural medicines and products are becoming increasingly important in the pharmaceutical
and food industries. The most important step in obtaining a natural remedy is the processing of
the natural material. This study offers the separation of the industrial hemp plant into fractions by
mechanical treatment, which has a significant impact on the selectivity of the obtained fractions. This
study also offers a solution to reduce waste by fractionating industrial hemp, focusing on the fraction
with the highest cannabinoid content (49.5% of CBD). The study confirmed the anticancer potential
of the extract, which prevents further division of WM-266-4 melanoma cells at a concentration of
10−3 mg/mL. However, application of the extract (c = 10−3 mg/mL) to normal human epidermal
melanocytes proved to be insignificant, as the metabolic activity of the cells was the same as in the
control cell group. |
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| Ključne besede: | supercritical fluid extraction, ultrasonic extraction, melanoma cells, extraction, WM-266-4 |
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| Status publikacije: | Objavljeno |
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| Verzija publikacije: | Objavljena publikacija |
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| Poslano v recenzijo: | 15.06.2022 |
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| Datum sprejetja članka: | 28.06.2022 |
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| Datum objave: | 30.06.2022 |
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| Založnik: | MDPI |
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| Leto izida: | 2022 |
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| Št. strani: | 14 str. |
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| Številčenje: | Vol. 11, iss. 13 |
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| PID: | 20.500.12556/DKUM-92747  |
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| UDK: | 66.02 |
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| COBISS.SI-ID: | 113614339 |
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| DOI: | 10.3390/plants11131749 |
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| ISSN pri članku: | 2223-7747 |
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| Avtorske pravice: | © 2022 by the authors |
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| Datum objave v DKUM: | 09.05.2025 |
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| Število ogledov: | 163 |
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| Število prenosov: | 15 |
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| Metapodatki: |    |
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| Področja: | Ostalo
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