| Title: | Chlorpyrifos detection based on 9-fluorenone oxime |
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| Authors: | ID Donà, Edoardo (Author)
ID Lobnik, Aleksandra (Author) |
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| Files: |  chemosensors-13-00170-v2.pdf (2,40 MB)
MD5: E8D3577EA27ABDEC84DE5EC4E607FF3A
 https://www.mdpi.com/2227-9040/13/5/170
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| Language: | English |
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| Work type: | Article |
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| Typology: | 1.01 - Original Scientific Article |
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| Organization: | FS - Faculty of Mechanical Engineering
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| Abstract: | Chlorpyrifos is one of the most toxic organophosphate pesticides, prompting its ban in Europe in 2020. Consequently, developing a detection method that is both selective and sensitive is essential for protecting human health and the environment. In this study, we report for the first time a fluorescent probe based on an oxime for the direct detection of chlorpyrifos. 9-fluorenone oxime, upon deprotonation with a phosphazene base, undergoes a nucleophilic attack on chlorpyrifos, resulting in a significant alteration of its fluorescence properties. Following careful optimization, the method demonstrated excellent linearity (R2 = 0.98) over a concentration range of 350 to 6980 μg/L, with a limit of detection of 15.5 μg/L. Furthermore, the probe was successfully applied to chlorpyrifos detection in water samples, yielding satisfactory results. This approach effectively overcomes the stability limitations of enzyme-based fluorescent sensors, offering a robust and innovative solution for the detection of organophosphate pesticides. |
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| Keywords: | organophosphate pesticide, chlorpyrifos, fluorenone oxime, fluorescence, phosphazene |
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| Publication status: | Published |
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| Publication version: | Version of Record |
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| Submitted for review: | 02.05.2025 |
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| Article acceptance date: | 02.05.2025 |
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| Publication date: | 06.05.2025 |
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| Publisher: | MDPI |
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| Year of publishing: | 2025 |
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| Number of pages: | 12 str. |
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| Numbering: | Vol. 13, iss. 5, [article no.] 170 |
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| PID: | 20.500.12556/DKUM-92936  |
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| UDC: | 544 |
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| ISSN on article: | 2227-9040 |
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| COBISS.SI-ID: | 237411075 |
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| DOI: | 10.3390/chemosensors13050170 |
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| Publication date in DKUM: | 27.05.2025 |
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| Views: | 181 |
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| Downloads: | 9 |
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| Metadata: |    |
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| Categories: | Misc.
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